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Muscle Metabolism During Exercise

Proceedings of a Karolinska Institutet Symposium held in Stockholm, Sweden, September 6–9, 1970 Honorary guest: E Hohwü Christensen

  • Conference proceedings
  • © 1971


Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 11)

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About this book

Howard G. Knuttgen of Biology, Boston University, 2 Cummington Department Street, Boston, 02215 Massachusetts, USA The relationship of the formation of lactate acid to skeletal muscle energy release in exercising humans was first explored by A. V. Hill and co-workers (2l, 22). The term "oxygen debt" was suggested by them to describe the excess oxygen consumption of recovery which they felt was closely related. A combination of their work and the earlier work of Krogh and Lindhard (35) re­ sulted at that time in the belief that a certain amount of energy release during the transition from rest to exercise was provided by a non-aerobic source, glycolysis. The resulting accumulation of lactic acid (as lactate) in the body required an extra con­ sumption during recovery for its oxidative removal. Jervell (24) subsequently showed that, in exercise, the greatest accumulation in blood took place during the first few minutes. He felt that the blood lactate increase was due to a shortage of oxygen during the transition period. The observation was also made for the first time that the increased level of lac­ tate due to exercise could be made to fall faster if mild exercise was employed by the subjects in place of sedentary recovery. The work of Margaria, Edwards and Dill (40) appeared in 1933. They observed that exercise (treadmill running) could be carried on at low levels without significant changes in resting levels of blood lactate.

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Table of contents (48 papers)

  1. Muscle Metabolism During Exercise in Man

  2. Adaptive Changes in Morphology and Enzymes of Skeletal Muscles

  3. Energy Stores (Magnitude, Regulation and Interaction)

    1. Release of Substrates from Extramuscular Stores During Exercise

    2. Uptake and Oxidation of Energy Rich Compounds in the Muscle During Exercise

Editors and Affiliations

  • Department of Clinical Physiology, Serafimerlasarettet, Karolinska Institutet, Stockholm, Sweden

    Bengt Pernow

  • Department of Physiology, Gymnastik & Idrottshögskolan, Stockholm, Sweden

    Bengt Saltin

Bibliographic Information

  • Book Title: Muscle Metabolism During Exercise

  • Book Subtitle: Proceedings of a Karolinska Institutet Symposium held in Stockholm, Sweden, September 6–9, 1970 Honorary guest: E Hohwü Christensen

  • Editors: Bengt Pernow, Bengt Saltin

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI:

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1971

  • Softcover ISBN: 978-1-4613-4611-1Published: 12 December 2012

  • eBook ISBN: 978-1-4613-4609-8Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVI, 558

  • Number of Illustrations: 19 b/w illustrations

  • Topics: Tree Biology

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