Comprehensive Virology

1. Front Matter

   Pages i-xvi

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2. Viral Invasion: Morphological, Biochemical, and Biophysical Aspects

   • C. Howe, J. E. Coward, T. W. Fenger

   Pages 1-71

3. Viral Persistence: Evolution of Viral Populations

   • Julius S. Youngner, Olivia T. Preble

   Pages 73-135

4. Defective Interfering RNA Viruses and the Host-Cell Response

   • John J. Holland, S. Ian T. Kennedy, Bert L. Semler, Charlotte L. Jones, Laurent Roux, Elizabeth A. Grabau

   Pages 137-192

5. Persistence and Transmission of Cytomegalovirus

   • Fred Rapp

   Pages 193-232

6. Aleutian Disease of Mink: A Model for Persistent Infection

   • David D. Porter, H. J. Cho

   Pages 233-256

7. Role of Viruses in Chronic Neurological Diseases

   • Jerry S. Wolinsky, Richard T. Johnson

   Pages 257-296

8. Host Plant Responses to Virus Infection

   • R. E. F. Matthews

   Pages 297-359

9. Back Matter

   Pages 361-372

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The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num­ bering, has probably reached that stage at which relatively few new­ truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua­ ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.

• genetics
• molecular biology
• virology

• Department of Molecular Biology and Virus Laboratory, University of California, Berkeley, USA

  Hein Fraenkael-Conrat

• Department of Microbiology, University of Virginia, Charlottesville, USA

  Robert R. Wagner

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