Advertisement

Mood Disorders

Toward a New Psychobiology

  • Peter C. Whybrow
  • Hagop S. Akiskal
  • William T. McKinneyJr.

Part of the Critical Issues in Psychiatry book series (CIPS)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Overview, History, and Classification of Mood Disorders

    1. Front Matter
      Pages 1-1
    2. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 3-19
    3. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 21-42
    4. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 43-63
  3. Elements of Present Knowledge

    1. Front Matter
      Pages 65-66
    2. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 67-80
    3. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 81-93
    4. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 95-117
    5. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 119-150
  4. Toward a Synthesis

    1. Front Matter
      Pages 151-151
    2. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 153-172
    3. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 173-203
    4. Peter C. Whybrow, Hagop S. Akiskal, William T. McKinney Jr.
      Pages 205-216
  5. Back Matter
    Pages 217-228

About this book

Introduction

In this book we present a conceptually integrated approach to disorders of mood. These disorders are defined narrowly as the clinical syndromes of mania and melancholia. The latter is our particular focus, for the simple reason that it is more common and thus more is known about it. Our approach owes much to Adolf Meyer, who first used the term psychobiology. It was he who emphasized in a practical way the importance of the clinician consider­ ing the joint contribution of psychosocial and biological factors in the genesis of mental disorders. However, until the 1960s, our relative ignorance of basic mechanisms that link brain and behavior prevented the development of a genuine psychobiological perspective. Thus Meyer's work was concerned largely with teaching the importance of the personal biography and a consideration of social history in the development of mental disorder. We feel that sufficiently rigorous data have now emerged in psychia­ try to permit tentative but real psychobiological integration. Affective illness is proba­ bly the most promising area for an attempt at such a synthesis. It is our belief that the theory and clinical practice of psychiatry now can be woven into a coherent theme, integrating insights and evidence generated by the psychodynamic, biological, and behavioral methods; hence in part we review the emerging psychobiology of mood disorders with the hope that it can serve as a generic paradigm for other psychiatric syndromes.

Keywords

Syndrom behavior brain mood disorder psychiatry syndromes

Authors and affiliations

  • Peter C. Whybrow
    • 1
  • Hagop S. Akiskal
    • 2
  • William T. McKinneyJr.
    • 3
  1. 1.University of Pennsylvania School of MedicinePhiladelphiaUSA
  2. 2.University of Tennessee College of Medicine and Baptist Memorial HospitalMemphisUSA
  3. 3.University of Wisconsin School of MedicineMadisonUSA

Bibliographic information