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Proteinuria

  • M. M. Avram

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Mechanisms of Proteinuria

    1. Front Matter
      Pages 1-2
    2. Barry M. Brenner, Lance D. Dworkin
      Pages 3-15
    3. C. Hyung Park, Maria Jose F. Camargo, Thomas Maack
      Pages 37-56
    4. John F. Maher
      Pages 57-65
    5. Roscoe R. Robinson
      Pages 67-79
  3. Clinical Expressions of Proteinuria

    1. Front Matter
      Pages 81-82
    2. John P. Hayslett
      Pages 83-92
    3. James M. Luciano, Aram V. Manoukian, Khalid M. H. Butt, Eli A. Friedman
      Pages 107-118
    4. Kurt H. Stenzel, Jhoong S. Cheigh, Janet Mouradian, John Wang, Ilene Miller
      Pages 119-126
    5. Ciril J. Godec
      Pages 127-132
  4. Pathophysiological Consequences and Management of Proteinuria

    1. Front Matter
      Pages 133-133
    2. George E. Schreiner
      Pages 153-161
  5. Expectant or Aggressive Management

    1. Front Matter
      Pages 163-164
    2. J. Sutton, D. E. Brown, A. J. Adler, J. E. Rubin, M. Seidman, E. A. Friedman et al.
      Pages 165-174
    3. Jerome G. Porush, Pierre F. Faubert
      Pages 175-193
    4. M. M. Avram
      Pages 195-207
    5. John E. Kiley, Gay Case, John D. Bower
      Pages 209-215
    6. Paul D. Doolan
      Pages 217-219
    7. Richard J. Glassock
      Pages 221-223
  6. Back Matter
    Pages 225-232

About this book

Introduction

Decoding the significance of proteinuria as an indicator of severity or prognosis in kidney disease is a stimulating challenge to students and practitioners of nephrology. Sir Richard Bright in 1827 associated pro­ with the disease that bears his name. In the subsequent more teinuria than a century and a half, however, the meaning of the linkage between proteinuria and renal disease remains elusive. Proteinuria is discovered on routine urinalysis in about 10 million Americans, most of whom express no symptoms of kidney disease, each year. From the studies of Robinson (updated in these pages), we know that proteinuria, per se, can be present for 20 years without change in re­ nal function, as described in orthostatic proteinuria. By contrast, pro­ teinuria may be the harbinger of swift kidney destruction, rarely cul­ minating in clinical collapse, a syndrome typifying "malignant proteinuria" as detailed herein by Avram. Although proteinuria is ubiquitous, an orderly management strategy for rational handling of proteinuria of less than nephrotic range is lack­ ing. Separation of tubular proteinuria and transient proteinuria of fever is now possible routinely. This book provides a record of the contribu­ tions of investigators and clinicians whose work forms the substrate for production of understanding and, ultimately, marching orders for prac­ titioners seeking optimized management for their proteinuric patients.

Keywords

kidney management nephrology

Editors and affiliations

  • M. M. Avram
    • 1
  1. 1.The Long Island College HospitalBrooklynUSA

Bibliographic information