Cell Membranes

Methods and Reviews Volume 3

  • Elliot Elson
  • William Frazier
  • Luis Glaser

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Jean-Loup Duband, Thierry Darribère, Jean-Claude Boucaut, Habib Boulekbache, Jean Paul Thiery
    Pages 1-53
  3. Richard A. Majack, Paul Bornstein
    Pages 55-77
  4. Gregory J. Cole, Richard W. Bond
    Pages 79-111
  5. Barry R. Ganong, Carson R. Loomis, Yusuf A. Hannun, Robert M. Bell
    Pages 183-214
  6. James R. Woodgett, Tony Hunter, Kathleen L. Gould
    Pages 215-340
  7. Back Matter
    Pages 407-417

About this book

Introduction

This volume assembles reviews on topics in two major related areas. One of these concerns the interactions of cells with substrata and with other cells, which are mediated by the extracellular matrix and soluble molecules. As described in this volume, these interactions are responsible for controlling cell functions ranging from embryogenesis and neural development to blood clotting. More­ over, important properties of the extracellular matrix can be modulated by the interdependent actions of tumor cells and fibroblasts. The other major area of interest concerns the response of cells to extracellular signals. Recent work has begun to reveal how a remarkable diversity of cellular functions, including neuronal, proliferative, membrane--cytoskeletal, and many other kinds of re­ sponses, are elicited through the mediation of a relatively small and interdepen­ dent set of second messenger systems. These include both changes in cytoplasmic ionic balances and activation of various kinds of protein kinases. Both subjects are covered in this volume. The two areas are linked by the common theme of cellular response to an external environment that is sensed through cellular interactions with informational molecules, which are soluble agents, as well as those that are components of insoluble matrices. It is only recently that we have come to appreciate the complex interplay between the matrix surrounding a cell and the cell's response to hormones and growth factors. Thus, we have tried to select examples in which this type of extracellular integration may playa role.

Keywords

Calcium Embryo Lipid Nucleotide cell growth enzymes gene expression smooth muscle tissue

Editors and affiliations

  • Elliot Elson
    • 1
  • William Frazier
    • 1
  • Luis Glaser
    • 2
  1. 1.Washington University School of MedicineSt. LouisUSA
  2. 2.University of MiamiCoral GablesUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4613-1915-3
  • Copyright Information Springer-Verlag US 1987
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-9065-0
  • Online ISBN 978-1-4613-1915-3
  • About this book