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Molecular Biology of Membrane Transport Disorders

  • Stanley G. Schultz
  • Thomas E. Andreoli
  • Arthur M. Brown
  • Douglas M. Fambrough
  • Joseph F. Hoffman
  • Michael J. Welsh

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Jonathan Covault
    Pages 11-45
  3. William P. Dubinsky, Otilia Mayorga-Wark
    Pages 73-86
  4. William A. Catterall
    Pages 129-145
  5. C. K. Ifune, Joe Henry Steinbach
    Pages 147-168
  6. David H. MacLennan, Michael S. Phillips, Yilin Zhang
    Pages 181-200
  7. Henry Sackin
    Pages 201-222
  8. Douglas M. Fambrough, Giuseppe Inesi
    Pages 223-241
  9. Michael M. Gottesman, Suresh V. Ambudkar, Marilyn M. Cornwell, Ira Pastan, Ursula A. Germann
    Pages 243-257
  10. Mark Donowitz, Susan A. Levine, C. H. Chris Yun, Steven R. Brant, Samir Nath, Jeannie Yip et al.
    Pages 259-275
  11. Ronald S. Kaplan
    Pages 277-302
  12. Victoria P. Knutson, Patricia V. Donnelly, Maria M. Lopez-Reyes, Yvonne L. O. Balba
    Pages 303-319
  13. Mariel Birnbaumer, Lutz Birnbaumer
    Pages 321-366
  14. Laurinda A. Jaffe
    Pages 367-378
  15. John R. Sachs
    Pages 379-406
  16. Orson W. Moe, Robert J. Alpern
    Pages 407-425
  17. William B. Busa
    Pages 427-446
  18. Lawrence G. Palmer
    Pages 447-468
  19. George Sachs, Jai Moo Shin, Krister Bamberg, Christian Prinz
    Pages 469-483
  20. Thomas J. Burke, Robert W. Schrier
    Pages 485-505
  21. John C. Parker
    Pages 507-517
  22. Piotr Zimniak, Roger Lester
    Pages 519-539
  23. Joseph H. Sellin
    Pages 541-563
  24. Henry J. Kaminski, Robert L. Ruff
    Pages 565-593
  25. Michael J. Welsh
    Pages 605-623
  26. Louis Ptáček, Robert C. Griggs
    Pages 625-642
  27. W. Brian Reeves, Thomas E. Andreoli
    Pages 643-657
  28. Back Matter
    Pages 659-681

About this book

Introduction

When the six of us gathered to start planning for what was to be the Third Edition of Physiology of Membrane Disorders, it was clear that since 1986, when the Second Edition appeared, the field had experienced the dawning of a new era dominated by a change in focus from phenomenology to underlying mechanisms propelled by the power of molecular biology. In 1985, detailed molecular information was available for only three membrane transporters: the lac permease, bacterial rhodopsin, and the acetylcholine receptor. During the decade that has since elapsed, almost all of the major ion channels and transport proteins have been cloned, sequenced, mutagenized, and expressed in homologous as well as heterologous cells. Few, if any, of the transporters that were identified during the previous era have escaped the probings of the new molecular technologies and, in many instances, considerable insight has been gained into their mechanisms of function in health and disease. Indeed, in some instances novel, unexpected transporters have emerged that have yet to have their functions identified. The decision to adopt the new title Molecular Biology of Membrane Transport Disorders was a natural outgrowth of these considerations.

Keywords

ATPase Biomembran Escherichia coli Pathogene Transporter cells erythrocyte molecular biology pathophysiology physiology signal transduction

Editors and affiliations

  • Stanley G. Schultz
    • 1
  • Thomas E. Andreoli
    • 2
  • Arthur M. Brown
    • 3
  • Douglas M. Fambrough
    • 4
  • Joseph F. Hoffman
    • 5
  • Michael J. Welsh
    • 6
  1. 1.University of Texas Medical School at HoustonHoustonUSA
  2. 2.University of Arkansas College of MedicineLittle RockUSA
  3. 3.Case Western Reserve UniversityClevelandUSA
  4. 4.The Johns Hopkins UniversityBaltimoreUSA
  5. 5.Yale University School of MedicineNew HavenUSA
  6. 6.University of Iowa College of MedicineIowa CityUSA

Bibliographic information