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Experimental Hepatocarcinogenesis

  • M. B. Roberfroid
  • V. Préat

Table of contents

  1. Front Matter
    Pages i-ix
  2. Experimental and Human Liver Carcinogenesis: Cause and Modulation

    1. Front Matter
      Pages 3-3
    2. Hans-Günther Neuman
      Pages 5-13
    3. Véronique Préat, Nathalie Delzenne
      Pages 41-50
    4. Stan D. Vesselinovitch, Nikola Mihailovich, Silvana Negri
      Pages 51-62
    5. Zsuzsa Schaff, Károly Lapis
      Pages 63-76
  3. Morphological Alterations During Liver Carcinogenesis

    1. Front Matter
      Pages 77-77
    2. Kurt Jungermann
      Pages 79-87
    3. Peter Bannasch, Harald Enzmann, Youbing Ruan, Edgar Weber, Heide Zerban
      Pages 89-103
    4. Hans Jörg Hacker, Gabriele Seelmann-Eggebert, Fritz Klimek, Peter Peschke, Rolf F. Kletzien
      Pages 105-118
  4. Cell Proliferation, Cell Death and Liver Carcinogenesis

    1. Front Matter
      Pages 119-119
    2. Hartmut M. Rabes
      Pages 121-132
    3. A. Columbano, G. M. Ledda-Columbano, P. Coni, D. S. R. Sarma, P. Pani
      Pages 133-141
    4. W. Bursch, R. Schulte-Hermann
      Pages 143-159
  5. Biochemical Alterations During Liver Carcinogenesis

    1. Front Matter
      Pages 161-161
    2. Lennart C. Eriksson, Pehr Rissler, Niclas Andersson, Christer Möller, Gunnar Norstedt, Göran Andersson
      Pages 175-184
    3. P. Pani, S. Dessì, B. Batetta
      Pages 185-193
    4. Francesco Feo, Renato Garcea, Lucia Daino, Rosa Pascale
      Pages 195-207
  6. Nuclear and Genetic Alterations during Liver Carcinogenesis

    1. Front Matter
      Pages 209-209
    2. H. Barbason, B. Bouzahzah, S. Massart, D. Brumioul, B. Robaye, Ch. Herens
      Pages 211-219
    3. Per O. Seglen, Gunnar Sæter, Per E. Schwarze
      Pages 221-229
    4. M. Kirsch-Volders, S. Haesen, A. Deleener, Ph. Castelain, H. Alexandre, V. Preat
      Pages 231-244
    5. C. Guguen-Guillouzo, G. Baffet, P. L. Etienne, D. Glaise, N. Defer, M. Corral et al.
      Pages 245-253
  7. In Vitro Studies in Liver Carcinogenesis

  8. Conclusions

  9. Back Matter
    Pages 313-321

About these proceedings

Introduction

The meeting on experimental hepatocarcinogenesis which took place in Spa, Belgium at the end of May 1987 was the Second European Meeting. About 100 scientists, mostly from Europe but also from the United States, met there for three days in a very friendly atmosphere to exchange knowledge and ideas on experimental and human liver carcinogenesis. The main topics discussed during the meeting included general reviews on hepatocarcinogenesis, experimental models of hepa­ tocarcinogenesis, biology of hepatocarcinogenesis, and in vitro studies in hepatocarcinogenesis. They are all covered by the various chapters of this proceedings volume, which reflects the present state of knowledge in this important field of cancer research. The final aim of that research is to understand the basic mechanisms of carcinogenesis. The liver offers a parti­ cularly interesting tool to reach such a goal. Indeed, its biochemistry, its morphology, and its physiology are very diverse, but relatively well known. Various protocols have been developed to produce hepatocellular carcinomas or other malignant tumors. Their appearance is most often preceded by phenotypically altered foci and nodules which have been isolated and characterized. The major cell populations of normal, neoplastic, and malignant livers have been cultivated.

Keywords

DNA apoptosis biology cancer carcinogenesis carcinoma cell cell death cellular differentiation chemistry hormones liver liver tumor tumor virus

Editors and affiliations

  • M. B. Roberfroid
    • 1
  • V. Préat
    • 1
  1. 1.Université Catholique de LouvainBrusselsBelgium

Bibliographic information