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Progress in Parkinson Research

  • Franz Hefti
  • William J. Weiner

Table of contents

  1. Front Matter
    Pages i-ix
  2. Stewart A. Factor, William J. Weiner
    Pages 1-10
  3. Lysia S. Forno
    Pages 11-21
  4. G. Frederick Wooten, Joel M. Trugman
    Pages 39-44
  5. R. G. MacKenzie, J. W. Kebabian
    Pages 53-60
  6. Jay A. Gingrich, Susan E. Senogles, Nourdine Amilaiky, Wei K. Chang, Joel G. Berger, Marc G. Caron
    Pages 67-76
  7. J. William Langston
    Pages 77-83
  8. S. P. Markey, H. Ikeda, S.-C. Yang, C. J. Markey, A. M. Marini, J. N. Johannessen
    Pages 85-91
  9. Sami I. Harik, Naji J. Riachi, Joseph C. LaManna
    Pages 93-100
  10. Stephen K. Younster, Richard E. Heikkila
    Pages 113-118
  11. Catherine Mytilineou, Linda K. Friedman, Peter Danias
    Pages 127-136
  12. Franz Hefti, Juan R. Sanchez-Ramos, Patrick P. Michel, Simon Efange, Berton C. Pressman
    Pages 137-143
  13. Juan R. Sanchez-Ramos, Franz Hefti, Gary E. Hollinden, Thomas J. Sick, Myron Rosenthal
    Pages 145-152
  14. Humberto B. Valdes, Doris Nonner, Dino Rulli, Leonard Gralnik, John Barrett
    Pages 163-171
  15. Caleb E. Finch
    Pages 173-179
  16. Don Marshall Gash, Massimo S. Fiandaca, Jeffrey H. Kordower, John T. Hansen
    Pages 181-186
  17. William J. Freed, Jill B. Becker
    Pages 197-204
  18. I. J. Kopin, K. S. Bankiewicz, R. J. Plunkett, L. Porrino, D. M. Jacobowitz, W. T. London et al.
    Pages 205-210
  19. T. J. Collier, D. E. Redmond Jr., R. H. Roth, J. D. Elsworth, J. R. Sladek Jr.
    Pages 211-218
  20. Ake Seiger, Lars Olson, Ingrid Stromberg, Marc Bygdeman, Menek Goldstein, Barry Hoffer
    Pages 219-223
  21. Back Matter
    Pages 225-228

About this book

Introduction

In the past five years significant progress has been made in our basic and clinical under­ standing of Parkinson's disease. The discovery that MPTP, a relatively simple molecule, is able to induce parkinsonism in otherwise healthy adult humans, and the recent interest in the possibility of "transplantation" procedures as a therapeutic modality in the treatment of Parkin­ son's disease have generated enormous interest in research related to Parkinson's disease. In this setting, the National Parkinson Foundation decided to organize a research meeting to bring together scientists actively engaged in research relevant to the study of Parkinson's disease, to accelerate its progress and to promote an exchange of ideas. This meeting took place in Janu­ ary 1988 at Key Biscayne, Florida. It was decided to publish the proceedings ofthis meeting to allow rapid documentation of the participants current findings and views regarding this rapidly of this volume follows the organization of the meeting and begins evolving field. The structure with a clinical and neuropathological review of current knowledge regarding Parkinson's dis­ ease. Since dopaminergic neurons playa major role in the pathophysiology of the disease, many of the contributions relate to some aspects of dopaminergic function including localiza­ tion, regulation, and pharmacology of dopamine receptors. A special effort has been made to provide a summary of the present knowledge of the cellular biology of the dopaminergic neurons.

Keywords

Parkinson behavior biochemistry biology brain cell cell culture environment neurons neuropathology pathology pharmacology physiology protein tissue

Editors and affiliations

  • Franz Hefti
    • 1
  • William J. Weiner
    • 1
  1. 1.National Parkinson FoundationMiamiUSA

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