Ir Genes
Past, Present, and Future
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Part of the Experimental Biology and Medicine book series (EBAM, volume 4)
Table of contents
About this book
Introduction
The Fifth Ir Gene Workshop was held at the Chase-Park Plaza Hotel, St. Louis, MO, August 28-31, 1982; 240 scientists participated in the Workshop. The man uscripts compiled in this book describe the state of the art concerning Ir genes. Although the notion of Ir Genes: Past, Present, and Future has not been ad dressed specifically by each author, the reader is certain to get this flavor from the contributions. In this Preface, we have tried to summarize some of the salient ob servations and discussions from the Workshop. The mUltiple genes of the I region have been defined traditionally by serolog ical analysis of intra-H-2 recombinant mice and the pattern of immune responses to certain antigens developed by these recombinant mice. The application of sev eral new techniques, such as gene cloning and DNA sequencing, production of T and B cell hybridomas, and development of cloned T cell lines has changed this tradition and introduced a new phase into the analysis of the I region, Ia antigens, and Ir genes.
Keywords
Antigen DNA Macrophages Monoclonal Antibodies T cell Vivo cell development gene genes genetics immune response immunity mutant regulation
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Bibliographic information
- DOI https://doi.org/10.1007/978-1-4612-5633-5
- Copyright Information Humana Press 1983
- Publisher Name Humana Press
- eBook Packages Springer Book Archive
- Print ISBN 978-1-4612-5635-9
- Online ISBN 978-1-4612-5633-5
- About this book