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Topics in Clinical Pharmacology and Therapeutics

  • Robert F. Maronde

Table of contents

  1. Front Matter
    Pages i-x
  2. Daniel C. Robinson
    Pages 1-12
  3. Alan Schumitzky
    Pages 13-25
  4. William P. Follansbee, James A. Shaver
    Pages 83-107
  5. Gary S. Francis, Jay N. Cohn
    Pages 135-150
  6. Jorge E. Valenzuela, Hartley Cohen
    Pages 151-174
  7. George T. Griffing, James C. Melby
    Pages 175-186
  8. Manuel T. Velasquez
    Pages 187-199
  9. William C. Cushman, Edward D. Freis
    Pages 200-215
  10. Robert F. Maronde, Daniel C. Robinson
    Pages 216-224
  11. Leon I. Goldberg, Sol I. Rajfer
    Pages 225-233
  12. Peter N. R. Heseltine, John M. Leedom
    Pages 250-287
  13. Thomas L. Petty
    Pages 352-357
  14. Thomas L. Petty
    Pages 358-366
  15. Leo E. Hollister
    Pages 367-381
  16. Philip D. Hansten
    Pages 382-396
  17. Hershel Jick
    Pages 397-404
  18. Margaret M. McCarron
    Pages 405-476
  19. David E. Smith, Richard B. Seymour
    Pages 477-493
  20. Jerry Avorn
    Pages 494-499
  21. Back Matter
    Pages 510-518

About this book

Introduction

Dr. Maronde has performed a major service in bringing together a superb array of scholars and clinicians to discuss not only the basic principles in therapeutics and clinical pharmacology but also the application of those principles to a wide range of clinical problems. Inclusion of chapters on adverse drug reactions, drug overdose, nonmedical prescription drug use, physician prescribing patterns, and the pharmaceutical industry makes this a particularly valuable book for clinicians. It is increasingly important that clinicians be well grounded in the principles of pharmacodynamics and pharmacokinetics because more and more of our patients are aging and cannot be treated as young or middle-aged adults. Elderly patients are liable to either drug overdose or underdose if traditional dosage formulas are followed because of changes in drug metabolism, drug distribution within the body, drug excretion, or changes in receptor site sensitivity. Because the elderly often present with mUltiple chronic diseases and require a variety of medications, they are more prone to medication errors, drug-drug interactions, and adverse drug reactions. The inclusion of three excellent chapters relating to drug-drug interactions, adverse drug reactions, and drug overdose is most welcome and is a valuable addition to this outstanding text on therapeutics and clinical pharmacology. Adverse drug reactions present a potentially serious problem for any patient for whom drugs are prescribed and particularly for those who must take multiple prescriptions.

Keywords

Clinical Therapeutics antibiotic asthma depression diagnosis drug infection kinetics metabolism pharmacodynamics pharmacokinetics pharmacology research shock

Editors and affiliations

  • Robert F. Maronde
    • 1
  1. 1.Clinical Pharmacology SectionUniversity of Southern California, School of MedicineLos AngelesUSA

Bibliographic information