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Drug Discovery and Development

  • Michael Williams
  • Jeffrey B. Malick

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Michael Williams, Jeffrey B. Malick
      Pages 3-29
  3. Compound Discovery

    1. Front Matter
      Pages 31-31
    2. John J. Baldwin
      Pages 33-71
    3. Philip Loftus, Marvin Waldman, Robert F. Hout Jr.
      Pages 73-96
    4. Jeffrey B. Malick
      Pages 115-149
    5. Ray W. Fuller, Larry R. Steranka
      Pages 177-198
    6. Steven C. Gilman, Alan J. Lewis
      Pages 227-256
  4. Toxicological Evaluation and Clinical Aspects

    1. Front Matter
      Pages 257-257
    2. Joy Cavagnaro, Richard M. Lewis
      Pages 259-289
    3. Joseph V. Bondi, D. G. Pope
      Pages 291-325
    4. Scott A. Reines, Dick Fong
      Pages 327-350
  5. Therapeutic Entities — From Discovery to Human Use

    1. Front Matter
      Pages 351-351
    2. Roger W. Brimblecombe, C. Robin Ganellin
      Pages 353-385
    3. Michael S. Eison, Duncan P. Taylor, Leslie A. Riblet
      Pages 387-407
    4. Robert J. Gould
      Pages 409-442
  6. Back Matter
    Pages 443-447

About this book

Keywords

autoimmune disease cannabinoid development drug drug discovery drugs dynamics ethanol methodology neurotoxicology neurotransmitter opioid pesticide research toxicity

Editors and affiliations

  • Michael Williams
    • 1
  • Jeffrey B. Malick
    • 2
  1. 1.Drug Discovery Administration, Pharmaceuticals DivisionCiba-Geigy CorporationSummitUSA
  2. 2.Biomedical Research Department, Stuart PharmaceuticalsICI Americas Inc.WilmingtonUSA

Bibliographic information