The Search for Bioactive Compounds from Microorganisms

  • Satoshi Ōmura

Part of the Brock/Springer Series in Contemporary Bioscience book series (BROCK/SPRINGER)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Antimicrobial Substances

    1. Front Matter
      Pages N1-N1
    2. Ruiko Ōiwa
      Pages 1-29
    3. Yoshitake Tanaka
      Pages 30-44
    4. Hideo Takeshima
      Pages 45-62
    5. Kazuhiko Otoguro, Haruo Tanaka
      Pages 63-78
  3. Antitumor Substances

    1. Front Matter
      Pages N2-N2
    2. Kanki Komiyama, Shinji Funayama
      Pages 79-103
    3. Haruki Yamada
      Pages 104-116
  4. Enzyme Inhibitors

    1. Front Matter
      Pages N3-N3
    2. Haruo Tanaka, Kazuhito Kawakita, Nobutaka Imamura, Kazuo Tsuzuki, Kazuro Shiomi
      Pages 117-160
  5. Pharmacologically Active Substances

    1. Front Matter
      Pages N4-N4
    2. Haruki Yamada
      Pages 171-197
    3. Akira Nakagawa
      Pages 198-212
  6. Agrochemicals

    1. Front Matter
      Pages N5-N5
    2. Shigenobu Okuda, Yoshitake Tanaka
      Pages 213-223
    3. Shigenobu Okuda
      Pages 224-236
    4. Yoshitake Tanaka, Shigenobu Okuda
      Pages 237-262
  7. Chemical Screening

    1. Front Matter
      Pages N6-N6
    2. Akira Nakagawa
      Pages 263-280
  8. Sources, Fermentation, and Improvement of Producing Microorganisms

    1. Front Matter
      Pages N7-N7
    2. Yuzuru Iwai, Yōko Takahashi
      Pages 281-302
  9. Back Matter
    Pages 337-353

About this book


Biologically active compounds isolated from microorganisms continue to be vital to the development of new drugs and agricultural chemicals. This book was prepared by current and past members of the laboratory of Dr. Satoshi Omura of the Kitasato Institute in Japan. Dr. Omura and his colleagues have discovered and studied a number of important antibiotics, and in their work they have pioneered new methods for screening microbes for interesting and important compounds. This book presents strategies and methods for identifying novel molecules with several types of biological activity. In addition, the book discusses the identification of microbial compounds of agrochemical importance, presents information on chemical screening methods, and concludes with chapters on microbial strain selection, fermentation technology, and genetic engineering of antibiotic-producing microorganisms. This book will be of great interest to scientists working in the very active and competitive fields of antibiotic and agrochemical discovery.


Fermentation antibiotic antibiotics antimicrobial bacteria cell cell differentiation development enzymes fungi genetic engineering insecticide microbe microorganism microorganisms

Editors and affiliations

  • Satoshi Ōmura
    • 1
  1. 1.Research Center for Biological Function, The Kitasato Institute, and School of Pharmaceutical SciencesKitasato UniversityMinato-ku, TokyoJapan

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag New York 1992
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-8761-2
  • Online ISBN 978-1-4612-4412-7
  • Series Print ISSN 1432-0061
  • Buy this book on publisher's site