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Controversies in Diabetes and Pregnancy

  • Lois Jovanovic

Part of the Endocrinology and Metabolism book series (EAM, volume 2)

Table of contents

  1. Front Matter
    Pages N1-xiv
  2. Animal Models for the Study of Diabetes and Pregnancy

    1. Front Matter
      Pages 1-1
  3. Islet Ontogeny: Fetal Pancreatic Ontogeny and Material Substrates

    1. Front Matter
      Pages 31-31
    2. Charles M. Peterson, Lois Jovanovic, Bent Formby
      Pages 43-53
  4. Optimal Management

    1. Front Matter
      Pages 55-55
    2. Edward J. Coetzee, W. P. U. Jackson
      Pages 57-76
    3. Barbara E. K. Klein
      Pages 77-89
    4. Lois Jovanovic, Charles M. Peterson
      Pages 90-100
    5. Raul Artal
      Pages 101-111
  5. Obstetrics Management

    1. Front Matter
      Pages 113-113
    2. Luis A. Bracero, Harold Schulman
      Pages 115-128
  6. Infant Outcome of Pregnancies Complicated by Diabetes

    1. Front Matter
      Pages 147-147
    2. Kathryn R. Slaine, Peter H. Bennett, David J. Pettitt
      Pages 172-189
  7. Back Matter
    Pages 191-205

About this book

Introduction

As I read this unique volume on diabetes and pregnancy edited by Lois Jovanovic, I was struck by two themes that run throughout these collected chapters. First, this volume provides an excellent assessment of past problems, present management, and future challenges presented by dia­ betes in pregnancy. Orury's unique, longitudinal experience with diabetes iIi pregnancy provides the reader with an important overview, as does Coetzee's discussion of gestational diabetes. Current problems-deter­ mining the etiology and prevention of congenital malformations in infants of diabetic mothers (10M), assessment of antepartum fetal condition, management of pregnant patients with diabetic retinopathy, recognition of thyroid dysfunction in the pregnant diabetic woman, and understanding the multitude of metabolic sequelae observed in the 10M-are thoroughly reviewed. Finally, important considerations for future treatment and ther­ apy such as the adaptation of the fetal pancreas to the disordered intra­ uterine environment often seen in maternal diabetes, the use of fetal pan­ creatic tissue for transplantation, the application of exercise in the management of the pregnant woman with diabetes, and the long-term con­ sequences for the 10M provide an exciting glimpse into the future. The second important theme that emerges is the critical role the problem of diabetes in pregnancy has played in our understanding of maternal and fetal physiology. Clinical observations supported by basic research have emphasized the role of fetal fuels in teratogenesis.

Keywords

Diabetes Pancreas adaptation obstetrics physiology pregnancy tissue

Editors and affiliations

  • Lois Jovanovic
    • 1
  1. 1.Sansum Medical Research FoundationSanta BarbaraUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4612-3792-1
  • Copyright Information Springer-Verlag New York Inc. 1988
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-8353-9
  • Online ISBN 978-1-4612-3792-1
  • Series Print ISSN 0938-040X
  • Buy this book on publisher's site