Oncogenes

An Introduction to the Concept of Cancer Genes

  • Kathy B. Burck
  • Edison T. Liu
  • James W. Larrick

Table of contents

  1. Front Matter
    Pages i-xv
  2. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 1-3
  3. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 4-37
  4. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 38-66
  5. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 67-77
  6. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 78-97
  7. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 98-132
  8. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 133-155
  9. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 156-181
  10. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 182-197
  11. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 198-221
  12. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 222-233
  13. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 234-240
  14. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 241-261
  15. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 262-278
  16. Kathy B. Burck, Edison T. Liu, James W. Larrick
    Pages 279-280
  17. Back Matter
    Pages 281-300

About this book

Introduction

"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat­ form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.

Keywords

Chromosom DNA cancer cell gene genes immunodeficiency leukemia molecular biology mutation oncogene tumor

Authors and affiliations

  • Kathy B. Burck
    • 1
  • Edison T. Liu
    • 2
  • James W. Larrick
    • 3
    • 4
  1. 1.Kasier Foundation HospitalSan FranciscoUSA
  2. 2.Lineberger Cancer Research CenterUniversity of North Carolina at Chapel HillChapel HillUSA
  3. 3.GENELABS, Inc.Redwood CityUSA
  4. 4.Psoriasis Research ScientistStanfordUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4612-3718-1
  • Copyright Information Springer-Verlag New York 1988
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-387-96423-2
  • Online ISBN 978-1-4612-3718-1
  • About this book