Fibronectins

  • Richard O. Hynes

Part of the Springer Series in Molecular Biology book series (SSMOL)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Richard O. Hynes
    Pages 1-6
  3. Richard O. Hynes
    Pages 7-23
  4. Richard O. Hynes
    Pages 24-48
  5. Richard O. Hynes
    Pages 49-83
  6. Richard O. Hynes
    Pages 84-112
  7. Richard O. Hynes
    Pages 113-175
  8. Richard O. Hynes
    Pages 176-199
  9. Richard O. Hynes
    Pages 200-230
  10. Richard O. Hynes
    Pages 231-248
  11. Richard O. Hynes
    Pages 249-280
  12. Richard O. Hynes
    Pages 281-300
  13. Richard O. Hynes
    Pages 301-334
  14. Richard O. Hynes
    Pages 335-348
  15. Richard O. Hynes
    Pages 349-364
  16. Richard O. Hynes
    Pages 380-392
  17. Back Matter
    Pages 393-546

About this book

Introduction

Fibronectins comprise a class of high molecular weight glycoproteins present both in extracellular matrices and in soluble form in body fluids. Although they have been studied for about forty years, their real significance emerged only during the past decade. Intensive research has focused on their role in platelet function, cell migration, the cytoskeleton, reticuloendothelial function, and on alterations in fibronectin distribution during development and disease. Fibronectins have emerged as glycoproteins with a very interesting set of properties generally involving adhesion of cells to cells or to extracellular material. In more recent years, the complete sequences of several fibronectin molecules and their genes were determined, the relation between structure and function was understood and much has been learned about cell surface receptors for fibronectins and other adhesive ligands. Having been at the forefront of all these exciting developments, the author has synthesized the entire field and with all the latest information at hand for the first time given it a clear perspective.

Keywords

Interferon Macrophages Migration Regulation Vivo developmental biology glycoprotein neutrophils proteins

Authors and affiliations

  • Richard O. Hynes
    • 1
  1. 1.Department of Biology Massachusetts Institute of TechnologyHoward Hughes Medical Institute and Center for Cancer ResearchCambridgeUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4612-3264-3
  • Copyright Information Springer-Verlag New York 1990
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-7940-2
  • Online ISBN 978-1-4612-3264-3
  • Series Print ISSN 0942-6523
  • About this book