Leukocyte Adhesion Molecules

  • Timothy A. Springer
  • Donald C. Anderson
  • Robert Rothlein
  • Alan S. Rosenthal
Conference proceedings

Table of contents

  1. Front Matter
    Pages i-xv
  2. Introduction

    1. Alan S. Rosenthal
      Pages 1-3
  3. Structure and Function of the Integrin Family

    1. Front Matter
      Pages 5-5
    2. Takashi K. Kishimoto, Richard S. Larson, Angel L. Corbi, Michael L. Dustin, Donald E. Staunton, Timothy A. Springer
      Pages 7-43
    3. Michael D. Pierschbacher, Pina M. Cardarelli
      Pages 58-71
    4. Jill P. Buyon, Mark R. Philips, Steven B. Abramson, Seth G. Slade, Gerald Weissmann, Robert Winchester
      Pages 72-83
  4. Adhesion in Disease and Therapy

    1. Front Matter
      Pages 85-85
    2. C. M. Doerschuk, R. K. Winn, J. M. Harlan
      Pages 87-94
    3. A. Fischer, B. Lisowska-Grospierre, F. Mazerolles, F. Le Deist, N. Perez, M. T. Dimanche-Boitrel et al.
      Pages 95-100
    4. Gunhild Lange Vejlsgaard, Nils Lauge Hansen, Elisabeth Ralfkiaer, Robert Rothlein
      Pages 101-105
    5. Douglas H. Jones, Frank C. Schmalstieg, Hal K. Hawkins, Bean L. Burr, Helen E. Rudloff, Sharon Krater et al.
      Pages 106-124
    6. Robert F. Todd III, Paul J. Simpson, Benedict R. Lucchesi
      Pages 125-137
    7. Elke Seewaldt-Becker, Robert Rothlein, Jürgen W. Dämmgen
      Pages 138-148
    8. Randall W. Barton, Robert Rothlein, John Ksiazek, Charles Kennedy
      Pages 149-155
  5. Myeloid Cell Adhesion

    1. Front Matter
      Pages 157-157
    2. Carl G. Figdor, Anje Te Velde, Jan E. De Vries
      Pages 159-169
    3. C. Wayne Smith, Steven D. Marlin, Robert Rothlein, Michael B. Lawrence, Larry V. McIntire, Donald C. Anderson
      Pages 170-189
    4. Samuel D. Wright, Siu Kong Lo, Patricia A. Detmers
      Pages 190-207
    5. Craig D. Wegner, C. Wayne Smith, Robert Rothlein
      Pages 208-214

About these proceedings

Introduction

Leukocyte adhesion molecules promise to be highly effective as antigens in the antibody-directed leucocyte elimination treatment prior to grafting or in cases of acute and chronic inflammatory disease. This comprehensive review of contemporary research provides thorough discussions of the structure of these molecules, their in vitro function, and the role that they play in vivo as evidenced by results shown in inflammatory models where antibodies against these molecules are given to inhibit their function. The blend of basic science and clinical applications provides clear evidence of the biological relevance of cell-cell interactions and the many potential clinical dividends afforded by understanding the molecular basis of cell adhesion.

Keywords

Antigen T cell cell immunosuppression lymphocytes receptor

Editors and affiliations

  • Timothy A. Springer
    • 1
  • Donald C. Anderson
    • 2
  • Robert Rothlein
    • 3
  • Alan S. Rosenthal
    • 4
  1. 1.Center for Blood Research, Harvard Medical SchoolBostonUSA
  2. 2.Pediatrics, Microbiology and Immunology, Head, Leukocyte Biology SectionBaylor College of Medicine and Texas Children’s HospitalHoustonUSA
  3. 3.Department of ImmunologyBoehringer Ingelheim Pharmaceuticals, Inc.RidgefieldUSA
  4. 4.Research & DevelopmentBoehringer Ingelheim Pharmaceuticals Inc.RidgefieldUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4612-3234-6
  • Copyright Information Springer-Verlag New York 1990
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-7927-3
  • Online ISBN 978-1-4612-3234-6
  • About this book