The P2 Nucleotide Receptors

  • John T. Turner
  • Gary A. Weisman
  • Jeffrey S. Fedan

Part of the The Receptors book series (REC)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Historical Perspectives of P2 Nucleotide Receptors

    1. Front Matter
      Pages 1-1
  3. Pharmalogical and Molecular Characterization of P2 Nucleotide Receptors

    1. Front Matter
      Pages 41-41
    2. Richard J. Evans, Annmarie Surprenant, R. Alan North
      Pages 43-61
    3. Gary A. Weisman, Fernando A. Gonzalez, Laurie Erb, Richard C. Garrad, John T. Turner
      Pages 63-79
    4. Kenneth A. Jacobson, Yong-Chul Kim, Emidio Camaioni, A. Michiel van Rhee
      Pages 81-107
    5. T. Kendall Harden, Robert A. Nicholas, Joel B. Schachter, Eduardo R. Lazarowski, José L. Boyer
      Pages 109-134
    6. A. Michiel van Rhee, Kenneth A. Jacobson, Richard Garrad, Gary A. Weisman, Laurie Erb
      Pages 135-166
  4. Mechanisms of P2 Nucleotide Receptor Action

    1. Front Matter
      Pages 167-167
    2. Jean-Marie Boeynaems, Didier Communi, Rodolphe Janssens, Serge Motte, Bernard Robaye, Sabine Pirotton
      Pages 169-183
    3. Charles Kennedy, Suzanne E. Hickman, Samuel C. Silverstein
      Pages 211-230
    4. Jeffrey S. Fedan
      Pages 231-255
  5. Physiological and Therapeutic Roles of P2 Nucleotide Receptors

    1. Front Matter
      Pages 257-257
    2. Eugene M. Silinsky, Ivar von Kügelgen, Andrew Smith, David P. Westfall
      Pages 259-290
    3. Sabine Pirotton, Claude Desgranges, Guy Vassort, Jean-Marie Boeynaems
      Pages 319-359
    4. Susanna Hourani, Francesco Di Virgilio, Marie-Madeleine Loubatières-Mariani
      Pages 361-411
    5. Scott H. Donaldson, Richard C. Boucher
      Pages 413-424

About this book

Introduction

In The P2 Nucleotide Receptors, leading researchers from major laboratories around the world summarize our current knowledge of the molecular biology, the physiology, and the pharmacology of the P2 receptors. Their authoritative contributions cover the major aspects of these receptors, describing the relationships between the physiological and pharmacological effects of ATP and other nucleotides and the various cloned P2 receptors, as well as providing an historical perspective and discussing current issues of nomenclature. They also illuminate how P2 receptor structures contribute to their function, including the physical differences underlying the pharmacological and functional variations among P2 receptor subtypes.

The critical survey and synthesis offered by The P2 Nucleotide Receptors lays a strong foundation for future work on P2 receptors-some no doubt yet to be cloned-as well as for establishing conclusively the identity of the cloned P2 receptor subtype(s) involved in the varied physiologic effects of extracellular nucleotides. With this broad coverage, the book immediately becomes today's single best source for understanding the major issues and future directions of P2 receptor research.

Keywords

molecular biology physiology platelets regulation smooth muscle tissue

Editors and affiliations

  • John T. Turner
    • 1
  • Gary A. Weisman
    • 1
  • Jeffrey S. Fedan
    • 2
  1. 1.Department of PharmacologyUniversity of Missouri-ColumbiaUSA
  2. 2.Physiology SectionNational Institute for Occupational Safety and HealthMorgantownUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4612-1800-5
  • Copyright Information Humana Press Inc. 1998
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-7289-2
  • Online ISBN 978-1-4612-1800-5
  • About this book