Autoimmune Reactions

  • Sudhir Paul

Part of the Contemporary Immunology book series (CONTIM)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Otto Pritsch, Guillaume Dighiero
    Pages 19-30
  3. Ramzi A. Ajjan, Anthony P. Weetman
    Pages 31-59
  4. Isao Nishimori, Michael A. Hollingsworth
    Pages 61-77
  5. Kenneth S. K. Tung, Kristine M. Garza, Ya-huan Lou
    Pages 99-112
  6. James W. Edinger, David N. Posnett
    Pages 113-140
  7. Constantin Bona, Chihiro Murai, Takeshi Sasaki
    Pages 141-155
  8. Haraldine A. Stafford, Morris Reichlin
    Pages 157-176
  9. Heinz Kohler, Sybille Müller
    Pages 191-199
  10. John J. Marchalonis, Samuel F. Schluter, David E. Yocum
    Pages 201-219
  11. Sudhir Paul
    Pages 221-234
  12. Gerald C. Groggel
    Pages 249-268
  13. Kumiko Yanase, Michael P. Madaio
    Pages 293-304

About this book

Introduction

Autoimmune Reactions tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itself and other "self" systems. The authoritative experts writing here explore the mechanistic aspects of such autoimmune diseases as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid disease, and where possible delineate how malfunctioning immunological mechanisms can lead to clinical symptoms. They also discuss possible general mechanisms of autoimmune disease-e.g., molecular mimicry and dysfunctional antigen presentation-and their current limitations as unifying explanations of the diseases described. In addition, evidence for novel immunological phenomena, including antibody catalysis and the penetration of cells by antibodies, is reviewed, and their possible biological consequences are identified. The book also critically surveys the concepts and research that should eventually permit development of palliatives and cures for autoimmune diseases, as well as approaches to the long-standing problem of self-nonself discrimination by the immune system.

The comprehensive, insightful overview provided in Autoimmune Reactions constitutes the new standard reference for all practicing autoimmunologists, molecular immunologists, cellular and molecular pathologists, and clinical immunologists who need to remain at the cutting-edge of research on autoimmune disease today.




Keywords

Antigen antigen presentation autoimmune disease autoimmunity cell diseases immunoglobulin pathogenesis proteins

Editors and affiliations

  • Sudhir Paul
    • 1
  1. 1.Department of Pathology and Laboratory Medicine, Health Sciences CenterUniversity of Texas Medical SchoolHoustonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4612-1610-0
  • Copyright Information Humana Press Inc. 1999
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-7215-1
  • Online ISBN 978-1-4612-1610-0
  • About this book