Skip to main content
  • Book
  • © 2014

Engineering in Translational Medicine


  • Covers a broad array of topics include cell engineering, nanoengineering, antibody/protein engineering, tissue engineering, and many others

  • Summarizes the state-of-the-art in the specific research area

  • Includes ample color figures

  • Includes supplementary material:

Buying options

eBook USD 219.00
Price excludes VAT (USA)
  • ISBN: 978-1-4471-4372-7
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 279.99
Price excludes VAT (USA)
Hardcover Book USD 349.99
Price excludes VAT (USA)

This is a preview of subscription content, access via your institution.

Table of contents (35 chapters)

  1. Front Matter

    Pages i-xix
  2. Cell and Tissue Engineering

    1. Front Matter

      Pages 17-17
    2. Stem Cells: The Holy Grail of Regenerative Medicine

      • Ram K. Singh, Snehal M. Gaikwad, Subhoshree Chatterjee, Pritha Ray
      Pages 19-69
    3. Engineering T Cells to Target Tumor Cells

      • Hiroki Torikai, Judy S. Moyes, Laurence J. N. Cooper
      Pages 71-101
    4. Structure, Function, and Development of Blood Vessels: Lessons for Tissue Engineering

      • Hamisha Ardalani, Amir H. Assadi, William L. Murphy
      Pages 155-182
  3. Genetic and Protein Engineering

    1. Front Matter

      Pages 201-201
    2. Engineering Luciferases for Assays and Imaging

      • Andreas M. Loening, Zachary F. Walls
      Pages 203-231
    3. Engineering Aspects of Bioluminescence Resonance Energy Transfer Systems

      • Abhijit De, Rohit Arora, Akshi Jasani
      Pages 257-300
    4. Antibody Engineering in Translational Medicine

      • Eliane Fischer
      Pages 301-316
    5. Engineered Affibodies in Translational Medicine

      • Xiang Hu, Hongguang Liu, Zhen Cheng
      Pages 317-342
    6. Engineering Multivalent and Multispecific Protein Therapeutics

      • Cassie J. Liu, Jennifer R. Cochran
      Pages 365-396
    7. Engineering Aptamers for Biomedical Applications: Part II

      • Laura Cerchia, Luciano Cellai, Vittorio de Franciscis
      Pages 427-447
    8. Engineering DNA Vaccines for Cancer Therapy

      • Brian M. Olson, Douglas G. McNeel
      Pages 449-471

About this book

This book covers a broad area of engineering research in translational medicine. Leaders in academic institutions around the world contributed focused chapters on a broad array of topics such as: cell and tissue engineering (6 chapters), genetic and protein engineering (10 chapters), nanoengineering (10 chapters), biomedical instrumentation (4 chapters), and theranostics and other novel approaches (4 chapters). Each chapter is a stand-alone review that summarizes the state-of-the-art of the specific research area.

Engineering in Translational Medicine gives readers a comprehensive and in-depth overview of a broad array of related research areas, making this an excellent reference book for scientists and students both new to engineering/translational medicine and currently working in this area.


  • Engineering of Clinical Imaging Systems
  • Nanoengineering
  • Protein Engineering
  • Stem Cell Engineering
  • Tissue Engineering
  • Translational Medicine


From the book reviews:

“This book may be considered an invaluable resource at first for scientists who want to have an updated overview of the whole scenario or a reference book to easily find information on the most advanced procedures. Furthermore, this publication may be very useful either for the training of students and residents, who may learn the fundamentals of translational medicine, or for the continuing education of clinicians already working in a medical practice.” (Luigi Mansi, European Journal of Nuclear Medicine and Molecular Medicine, Vol. 41, 2014)

"This book brings together many diverse yet related topics to give the reader a solid overview of many important areas that are not found together elsewhere. Dr. Weibo Cai has taken great care to select key research leaders of many sub-disciplines who have put together very detailed chapters that are easy to read yet highly rich in content. It is very exciting to see such a great set of chapters all together to allow one to have a key understanding of many different areas including cell, gene, protein, and nano engineering as well as the emerging field of theranostics. I am sure the readers will find this collection of important chapters helpful in their own research and understanding of how engineering has and will continue to play a critical role in biomedical research and clinical translation." (Sanjiv Sam Gambhir M.D., Ph.D., Stanford University, USA)

"Engineering in Translational Medicine is a landmark book bridging the fields of engineering and medicine with a focus on translational technologies and methods. In a single, well-coordinated volume, this book brings together contributions from a strong and international scientific cast, broadly covering the topics. The book captures the tremendous opportunities made possible by recent developments in bioengineering, and highlights the potential impact of these advances across a broad spectrum of pressing health care needs. The book can equally serve as a text for graduate level courses, a reference source, a book to be dipped into for pleasure by those working within the field, or a cover-to-cover read for those wanting a comprehensive, yet readable introduction to the current state of engineering advances and how they are impacting translational medicine." (Simon R. Cherry, Ph.D., University of California, Davis, USA)

Editors and Affiliations

  • Dept of Radiology/Medical Physics/Biomed, University of Wisconsin, Madison, USA

    Weibo Cai

About the editor

Dr. Weibo Cai is an Assistant Professor of Radiology, Medical Physics, and Biomedical Engineering at the University of Wisconsin - Madison. After receiving a PhD degree in Chemistry from UCSD in 2004, Dr. Cai did his post-doctoral research at the Molecular Imaging Program at Stanford University. In February 2008, Dr. Cai joined the University of Wisconsin - Madison as a Biomedical Engineering Cluster Hire, and his research is focused on molecular imaging and nanotechnology (

Dr. Cai has authored >120 peer-reviewed articles (total citation: >6,000; H-index: 39), >10 book chapters, and guest-edited many special topic issues for peer-reviewed journals. Dr. Cai has served on the Editorial Board of >20 journals, performed peer-review for >100 journals, participated in many grant review panels, chaired many sessions of international conferences, among others. Dr. Cai is currently the Executive Editor of the American Journal of Nuclear Medicine and Molecular Imaging (

Dr. Cai has received many prestigious awards, including the Society of Nuclear Medicine and Molecular Imaging (SNMMI) Young Professionals Committee Best Basic Science Award (2007), European Association of Nuclear Medicine Springer Prize (2011), American Cancer Society Research Scholar (2013-2017), among many others. Trainees in the Cai group at UW - Madison have received >20 Awards, including a 2012 SNMMI Berson-Yalow Award, 2012 SNMMI Radiopharmaceutical Sciences Council Young Investigator Award, 2013 SNMMI Cardiovascular Council Young Investigator Award, DOD BCRP Post-doctoral Fellowship (2011-2014), and ~10 travel awards to international scientific conferences.

Bibliographic Information

Buying options

eBook USD 219.00
Price excludes VAT (USA)
  • ISBN: 978-1-4471-4372-7
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 279.99
Price excludes VAT (USA)
Hardcover Book USD 349.99
Price excludes VAT (USA)