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Tumours of the Nervous System

an Ultrastructural Atlas

  • T. H. Moss

Table of contents

  1. Front Matter
    Pages i-x
  2. T. H. Moss
    Pages 1-8
  3. T. H. Moss
    Pages 9-15
  4. T. H. Moss
    Pages 17-23
  5. T. H. Moss
    Pages 25-29
  6. T. H. Moss
    Pages 31-36
  7. T. H. Moss
    Pages 37-41
  8. T. H. Moss
    Pages 43-49
  9. T. H. Moss
    Pages 51-55
  10. T. H. Moss
    Pages 57-65
  11. T. H. Moss
    Pages 67-73
  12. T. H. Moss
    Pages 75-80
  13. T. H. Moss
    Pages 81-84
  14. T. H. Moss
    Pages 85-91
  15. T. H. Moss
    Pages 93-97
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    Pages 99-105
  17. T. H. Moss
    Pages 107-111
  18. T. H. Moss
    Pages 113-118
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    Pages 119-122
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    Pages 123-127
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    Pages 129-133
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    Pages 135-143
  23. T. H. Moss
    Pages 145-149
  24. T. H. Moss
    Pages 151-154
  25. T. H. Moss
    Pages 155-160
  26. Back Matter
    Pages 161-166

About this book

Introduction

Since the time of the earliest electron microscopic studies on tumours of the human nervous system. undertaken over 20 years ago by Luse and her colleagues. there have been considerable advances in our understanding of these neoplasms. Tissue culture and specific antibodies to tumour antigens are two of the techniques which have greatly aided such advances. enabling much to be learned about the biological properties and underly­ ing nature of all types of nervous system tumour. Electron microscopy. however. has continued to prove of considerable value in the investigation of these tumours. and the technological advances of the last two decades have dramatically improved the resolution and overall quality of the ultrastructural images obtained. In clinical neuropathology. such improvements have encouraged a more widespread use of the electron microscope in the diagnosis of human nervous system tumours. alongside antibody techniques and more conventional histological methods. Although ultrastructural examination is often not strictly necessary to identify well-differentiated tumours such as astrocytomas or choroid plexus papillomas. study of the electron microscopic features in such cases fre­ quently proves useful in the diagnosis of their more malignant counterparts. Thus the recognition of astrocytic filaments in anaplastic gliomas. or of cilia in pleomorphic choroid plexus carcinomas. may enable a diagnosis to be made in cases where there is insufficient differentiation for the tumours to be recognised at light microscopic level.

Keywords

carcinoma cognition diagnosis electron microscopy nervous system neuropathology pathology tissue tumor

Authors and affiliations

  • T. H. Moss
    • 1
  1. 1.Department of NeuropathologyFrenchay HospitalBristolUK

Bibliographic information