Advertisement

Drug Product Development for the Back of the Eye

  • Uday B. Kompella
  • Henry F. Edelhauser

Part of the AAPS Advances in the Pharmaceutical Sciences Series book series (AAPS, volume 2)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Ravi D. Vaishya, Hari Krishna Ananthula, Ashim K. Mitra
    Pages 21-45
  3. Bernard E. McCarey
    Pages 47-84
  4. Masanori Tachikawa, Vadivel Ganapathy, Ken-ichi Hosoya
    Pages 85-109
  5. Thomas Gadek, Dennis Lee
    Pages 111-124
  6. Clive G. Wilson, Lay Ean Tan, Jenifer Mains
    Pages 125-158
  7. Dayle H. Geroski, Henry F. Edelhauser
    Pages 159-171
  8. Timothy W. Olsen, Brian C. Gilger
    Pages 173-184
  9. Susan S. Lee, Patrick Hughes, Aron D. Ross, Michael R. Robinson
    Pages 185-230
  10. Shelley A. Durazo, Uday B. Kompella
    Pages 261-290
  11. Gauri P. Misra, Thomas W. Gardner, Tao L. Lowe
    Pages 291-304
  12. Samirkumar R. Patel, Henry F. Edelhauser, Mark R. Prausnitz
    Pages 331-360
  13. Francine F. Behar-Cohen, Peter Milne, Jean-Marie Parel, Indu Persaud
    Pages 361-390
  14. John M. Nickerson, Jeffrey H. Boatright
    Pages 391-408
  15. Rinku Baid, Puneet Tyagi, Shelley A. Durazo, Uday B. Kompella
    Pages 409-448
  16. Jithan Aukunuru, Puneet Tyagi, Chandrasekar Durairaj, Uday B. Kompella
    Pages 449-468
  17. Robert I. Scheinman, Sunil K. Vooturi, Uday B. Kompella
    Pages 495-563
  18. Stephanie L. Foster, Cristina Kendall, Allia K. Lindsay, Alison C. Ziesel, Rachael S. Allen, Sheree S. Mosley et al.
    Pages 565-576
  19. Back Matter
    Pages 577-590

About this book

Introduction

This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include:

  • Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms
  • Refillable and microneedle devices
  • Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery
  • Physical methods including iontophoresis for drug delivery
  • Rational selection of routes of administration and delivery systems
  • Noninvasive and continuous drug monitoring
  • Clinical endpoints and regulatory path to drug product development
  • Emerging and existing drugs and drug targets

 

Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering.

 

Uday B. Kompella, Ph.D., Professor of Pharmaceutical Sciences & Ophthalmology, University of Colorado, developed functionalized nanoparticles, nanoporous microparticles, microparticles, injectable implants, dendrimers, liposomes, and in situ forming gels for the eye. He is a Fellow of the American Association of Pharmaceutical Scientists (2005) and the Association for Research in Vision and Ophthalmology (2010). He received Distinguished Scientist (2006) Award from the University of Nebraska.

 

Henry F. Edelhauser, Ph.D., Professor of Ophthalmology, Emory University, made pioneering contributions towards transcorneal, transscleral, and suprachoroidal drug delivery to the eye. He is a recipient of the Castroviejo Medal and the Alcon Research Award (1999), American Academy of Ophthalmology Senior Achievement Award (2000), and the Procter Medal (2005) for his outstanding ophthalmic translational research. He served as the president of the Association for Research in Vision and Ophthalmology (1990-91).

Keywords

AAPS Back Development Drug Edelhauser Eye Kompella Product

Editors and affiliations

  • Uday B. Kompella
    • 1
  • Henry F. Edelhauser
    • 2
  1. 1.School of PharmacyUniversity of Colorado DenverAuroraUSA
  2. 2.School of MedicineEmory UniversityAtlantaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4419-9920-7
  • Copyright Information American Association of Pharmaceutical Scientists 2011
  • Publisher Name Springer, Boston, MA
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4419-9919-1
  • Online ISBN 978-1-4419-9920-7
  • Series Print ISSN 2210-7371
  • Series Online ISSN 2210-738X
  • Buy this book on publisher's site