Book 2011

The Science and Business of Drug Discovery

Demystifying the Jargon

Authors:

ISBN: 978-1-4419-9901-6 (Print) 978-1-4419-9902-3 (Online)

Table of contents (20 chapters)

  1. Front Matter

    Pages i-xvii

  2. No Access

    Chapter

    Pages 1-7

    Introduction

  3. Background to Drug Discovery and Development

    1. Front Matter

      Pages 9-9

    2. No Access

      Chapter

      Pages 11-27

      Introduction to Drugs and Drug Targets

    3. No Access

      Chapter

      Pages 29-55

      Background to Chemistry of Small and Large Molecules

    4. No Access

      Chapter

      Pages 57-90

      Laying the Foundations: Drug Discovery from Antiquity to the Twenty-First Century

  4. The Drug Development Pipeline: Discovery to Testing in Humans

    1. Front Matter

      Pages 91-91

    2. No Access

      Chapter

      Pages 93-95

      Drug Discovery Pipeline Overview

    3. No Access

      Chapter

      Pages 97-137

      Target Discovery

    4. No Access

      Chapter

      Pages 139-158

      Medicinal Chemistry

    5. No Access

      Chapter

      Pages 159-177

      Biotherapeutics

    6. No Access

      Chapter

      Pages 179-189

      Screening for Hits

    7. No Access

      Chapter

      Pages 191-202

      Process Chemistry and Formulation

    8. No Access

      Chapter

      Pages 203-225

      Preclinical Development

  5. The Drug Development Pipeline: Clinical Trials to Marketing Authorization

    1. Front Matter

      Pages 227-227

    2. No Access

      Chapter

      Pages 229-253

      Clinical Trials

    3. No Access

      Chapter

      Pages 255-267

      Regulatory Affairs and Marketing Approval

    4. No Access

      Chapter

      Pages 269-289

      Diagnostics and Personalized Medicine

    5. No Access

      Chapter

      Pages 291-302

      Pulling It All Together: A Drug Development Case History

  6. The Global Pharmaceuticals Business

    1. Front Matter

      Pages 303-303

    2. No Access

      Chapter

      Pages 305-328

      Commercial Aspects of Drug Development

    3. No Access

      Chapter

      Pages 329-347

      Challenges and Responses

  7. Professional Interactions with the Drug Discovery Industry

    1. Front Matter

      Pages 349-349

    2. No Access

      Chapter

      Pages 351-358

      Technology Transfer Executives

    3. No Access

      Chapter

      Pages 359-362

      Recruitment Executives

    4. No Access

      Chapter

      Pages 363-367

      Pharmaceutical Translators and Interpreters

  8. Back Matter

    Pages 369-397