Signaling in the Heart

  • José Marín-García

Table of contents

  1. Front Matter
    Pages i-xx
  2. Methodologies

    1. Front Matter
      Pages 1-1
    2. José Marín-García
      Pages 3-18
  3. Normal Signaling Processes

    1. Front Matter
      Pages 19-19
    2. José Marín-García
      Pages 31-48
    3. José Marín-García
      Pages 49-68
    4. José Marín-García
      Pages 69-85
    5. José Marín-García
      Pages 87-97
    6. José Marín-García
      Pages 99-122
  4. Mitochondria

    1. Front Matter
      Pages 123-123
  5. Pediatric Cardiology

    1. Front Matter
      Pages 153-153
    2. José Marín-García
      Pages 155-196
    3. José Marín-García
      Pages 197-217
  6. Aging

    1. Front Matter
      Pages 219-219
    2. José Marín-García
      Pages 221-243
  7. Signaling in Cardiovascular Disease

    1. Front Matter
      Pages 245-245
    2. José Marín-García
      Pages 247-256
    3. José Marín-García
      Pages 257-270

About this book


Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology.  The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome.  Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact.

This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions.  Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology.  It is an invaluable reference for cardiology researchers and practitioners.


Cardiovascular Myocardium Pathways Signaling Vasculature

Authors and affiliations

  • José Marín-García
    • 1
  1. 1.Neuromuscular InstituteMolecular Cardiology &Highland ParkUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine
  • Print ISBN 978-1-4419-9460-8
  • Online ISBN 978-1-4419-9461-5
  • About this book