ADP-Ribosylation Reactions

  • Guy G. Poirier
  • Pierre Moreau

Table of contents

  1. Front Matter
    Pages i-xxxvi
  2. Molecular Biology

    1. Front Matter
      Pages 1-1
    2. Miguel Molinete, Valérie Schreiber, Frédéric Simonin, Gérard Gradwohl, Josiane Ménissier-de Murcia, Gilbert de Murcia
      Pages 3-13
    3. Masanao Miwa, Youichi Ozawa, Masako Uchida, Shigeki Kushida, Yoshihiro Ami, Masayuki Matsumura et al.
      Pages 14-19
    4. M. Schweiger, B. Auer, H. Herzog, M. Hirsch-Kauffman, P. Kaiser, K. Flick et al.
      Pages 20-29
    5. G. T. Marsischky, M. Ikejima, H. Suzuki, T. Sugimura, H. Esumi, M. Miwa et al.
      Pages 47-52
    6. Claude P. Niedergang, Jean-Marie Garnier, Jean-Marc Jeltsch, Marie-Elisabeth Ittel
      Pages 53-57
    7. Magali G. Chabert, Claude P. Niedergang, Fernand Hog, Mariagrazia Partisani, Paul Mandel
      Pages 58-61
    8. H. Berghammer, M. Schweiger, B. Auer
      Pages 69-72
    9. Veronica Kang, Saikh J. Haque, Barry Cherney, Mark Smulson
      Pages 73-76
    10. Barry Cherney, Kishor Bhatia, Bushra Chaudhry, Tauseef Butt, Mark Danielsen, Mark Smulson
      Pages 77-80
    11. Marta Menegazzi, Alessandra Carcereri De Prati, Tsutomu Ogura, Amedeo Columbano, Giovanna Maria Ledda-Columbano, Palmiro Poltronieri et al.
      Pages 86-91
    12. Pierre Moreau, Guy Poirier, Scott Kaufmann
      Pages 92-94
  3. Cancer, DNA Repair, and Metabolism

    1. Front Matter
      Pages 95-95
    2. Malcolm C. Paterson, Michel Liuzzi, Anne M. Galloway, John R. A. Chan, Michael V. Middlestadt, Michael Weinfeld et al.
      Pages 97-105
    3. B. Saulier, F. Simonin, G. Gradwohl, G. de Murcia, M. Philippe
      Pages 106-112

About these proceedings


This monograph is dedicated to one of the discoverers of poly(ADP­ ribose), Professor Paul Mandel, from the Centre de Neurochimie in Strasbourg. We would like to congratulate him for his distinguished contributions to the field of poly(ADP-ribosyl)ation and express our gratitude for his support in the last years and particularly for his encouragement for the organization of this meeting. Poly(ADP-ribose) was discovered more than 25 years ago. Since then, excellent progress has been made on the study of the mechanisms of poly(ADP­ ribose) reaction. The last five years have been particularly exciting since the development of various molecular biology techniques has revealed the complex nature of this multifunctional enzyme. Looking at the contributions presented at this meeting, it becomes obvious that more work at the molecular level is needed. Most likely, these experiments will shed some light on the functions of poly(ADP-ribose), but further ~iophysical studies will still be required to fully understand this complex enzymatic system.


Calcium Chloroplast DNA Nucleotide base biology enzyme enzymes gene expression metabolism molecular biology oncogene pharmacology protein synthesis

Editors and affiliations

  • Guy G. Poirier
    • 1
  • Pierre Moreau
    • 2
  1. 1.Centre de Recherches en Endocrinologie MoleculaireLe Centre Hospitalier de l’Universite LavalCanada
  2. 2.Biochemistry Department Pavillon VachonUniversite LavalCanada

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 1992
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-6456-9
  • Online ISBN 978-1-4419-8718-1
  • About this book