Environmental Radiation Effects on Mammals

A Dynamical Modeling Approach

  • Olga A.┬áSmirnova

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Olga A. Smirnova
    Pages 1-6
  3. Olga A. Smirnova
    Pages 7-99
  4. Olga A. Smirnova
    Pages 101-119
  5. Olga A. Smirnova
    Pages 121-149
  6. Olga A. Smirnova
    Pages 151-169
  7. Back Matter
    Pages 211-214

About this book

Introduction

This text is devoted to the theoretical studies of radiation effects on mammals. It uses the framework of developed deterministic mathematical models to investigate the effects of both acute and chronic irradiation in a wide range of doses and dose rates on vital body systems including hematopoiesis, small intestine and humoral immunity, as well as on the development of autoimmune diseases. Thus, these models can contribute to the development of the system and quantitative approaches in radiation biology and ecology. This text is also of practical use. Its modeling studies of the dynamics of granulocytopoiesis and thrombocytopoiesis in humans testify to the efficiency of employment of the developed models in the investigation and prediction of radiation effects on these hematopoietic lines. These models, as well as the properly identified models of other vital body systems, could provide a better understanding of the radiation risks to health. The modeling predictions will enable the implementation of more effective preventive and protective measures for people residing in areas with elevated radiation background and astronauts on long-term space missions. Lastly, the models of the radiation-induced mortality established the theoretical foundations of a new individual-based approach to radiation risk assessment. These models thus enable one to predict the mortality dynamics and average life-span shortening for individuals and populations exposed to acute and low-level chronic radiation. Because of its theoretical and practical benefits, this book is as useful for academics, scientists and researchers working in the field of mathematical modeling of biological systems as it is for those working in the fields of radiation biology, ecology and medicine. It is equally useful for Aerospace companies and various corporations that contend with the problems of environmental protection and radiation safety.

Keywords

Illnesses caused by radiation in space Mathematical modeling in life sciences Radiation biology and ecology Radiation risk assesment mathematical modeling risk assessment of space missions

Authors and affiliations

  • Olga A.┬áSmirnova
    • 1
  1. 1.Research Centre of Spacecraft, Radiation Safety of the HealthMinistry of RussiaMoskvaRussian Federation

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4419-7213-2
  • Copyright Information Springer Science+Business Media, LLC 2010
  • Publisher Name Springer, New York, NY
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-1-4419-7212-5
  • Online ISBN 978-1-4419-7213-2
  • About this book