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The Genetics and Development of Scoliosis

  • Book
  • © 2010

Overview

Editors:
  1. Kenro Kusumi

    1. School of Life Sciences, Arizona State University, Tempe, U.S.A.

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    You can also search for this editor in PubMed   Google Scholar

  2. Sally L. Dunwoodie

    1. St. Vincent's Hospital, Darlinghurst, Australia

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  • Written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine

  • Recent developments in clinical and molecular genetic studies of these disorders are also discussed

  • Includes supplementary material: sn.pub/extras

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xii
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  2. Genetic Regulation of Somite and Early Spinal Patterning

    • Kenro Kusumi, Walter Eckalbar, Olivier Pourquié
    Pages 1-20

  3. Development and Functional Anatomy of the Spine

    • Alan Rawls, Rebecca E. Fisher
    Pages 21-46

  4. Environmental Factors and Axial Skeletal Dysmorphogenesis

    • Peter G. Alexander, Rocky S. Tuan
    Pages 47-72

  5. Overview and Comparison of Idiopathic, Neuromuscular, and Congenital Forms of Scoliosis

    • Benjamin Alman
    Pages 73-79

  6. Abnormal Vertebral Segmentation (or Segmentation Defects of the Vertebrae) and the Spondylocostal Dysostoses

    • Peter D. Turnpenny
    Pages 81-108

  7. Spondylothoracic Dysostosis in Puerto Rico

    • Alberto Santiago Cornier
    Pages 109-126

  8. Progress in Understanding Genetic Contributions in Syndromic and Non-Syndromic Disorders Associated with Congenital, Neuromuscular, and Idiopathic Scoliosis

    • Philip F. Giampietro
    Pages 127-152

  9. Genetics and Functional Pathology of Idiopathic Scoliosis

    • Nancy H. Miller
    Pages 153-166

  10. Current Understanding of Genetic Factors in Idiopathic Scoliosis

    • Carol A. Wise, Swarkar Sharma
    Pages 167-190

  11. Conclusion: Trends and Predictions for Genetic and Developmental Biological Research on Scoliosis

    • Kenro Kusumi
    Pages 191-198

  12. Back Matter

    Pages 199-218
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Keywords

About this book

Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.

Editors and Affiliations

  • School of Life Sciences, Arizona State University, Tempe, U.S.A.

    Kenro Kusumi

  • St. Vincent's Hospital, Darlinghurst, Australia

    Sally L. Dunwoodie

About the editors

Kenro Kusumi, Ph.D., is an Associate Professor in the School of Life Sciences at Arizona State University and is a founding faculty member at the new University of Arizona College of Medicine-Phoenix in partnership with Arizona State University. Dr. Kusumi’s current research focuses on early spinal development, axial musculoskeletal regeneration, and their applications to genetic studies of scoliosis and other musculoskeletal disorders.

Sally L. Dunwoodie, Ph.D., is an Associate Professor at the University of New South Wales and Laboratory Head in the Developmental Biology Division at the Victor Chang Cardiac Research Institute in Sydney. Dr Dunwoodie's research focuses on development of the spine, heart, kidney and placenta in mouse, and their relevance to the molecular basis of congenital abnormalities.

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