Overview
Will cover many of the recent findings in the area of senescence and cancer, including chapters that discuss telomeres and senescence signals, the senescent phenotype, and the physiological effects of senescence, including therapeutic applications
Includes supplementary material: sn.pub/extras
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Table of contents (10 chapters)
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Front Matter
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The senescent phenotype
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Front Matter
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The physiological consequences of senescence
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Front Matter
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Back Matter
Keywords
About this book
As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.
Editors and Affiliations
Bibliographic Information
Book Title: Cellular Senescence and Tumor Suppression
Editors: Peter D. Adams, John M. Sedivy
DOI: https://doi.org/10.1007/978-1-4419-1075-2
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag New York 2010
Hardcover ISBN: 978-1-4419-1074-5Published: 17 December 2009
Softcover ISBN: 978-1-4899-8356-5Published: 30 November 2014
eBook ISBN: 978-1-4419-1075-2Published: 23 January 2010
Edition Number: 1
Number of Pages: XIII, 272
Topics: Cancer Research, Human Genetics, Pharmacology/Toxicology