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  • © 2009

Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome

  • Concepts and emergent therapeutic interventions

  • Oxidative stress molecules in metabolic syndrome

  • Evidence of Inflammatory pathways in metabolic syndrome

  • Neovascular pathways in metabolic syndrome

  • Cross-talk between the three processes in metabolic syndrome

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Table of contents (9 chapters)

  1. Front Matter

    Pages I-X
  2. The Metabolic Syndrome

    • Ana Azevedo, Ana C. Santos, Laura Ribeiro, Isabel Azevedo
    Pages 1-19
  3. Oxidative Stress in the Metabolic Syndrome

    • Conceição Calhau, Alejandro Santos
    Pages 33-63
  4. Angiogenesis in the Metabolic Syndrome

    • Raquel Soares
    Pages 85-99
  5. Vascular Glucose Transport and the Metabolic Syndrome

    • Fatima Martel, Elisa Keating
    Pages 123-146
  6. Back Matter

    Pages 187-209

About this book

Metabolic Syndrome (MS) is a highly prevalent condition in developed countries and is a cluster of several risk factors for type 2 diabetes and cardiovascular disease that includes increased body mass index/waist circumference, visceral obesity, insulin resistance, hyperclycaemia, dyslipidaemia and hypertension, which are all major causes of morbidity and death.

This volume provides a critical review and discussion of the knowledge gathered on MS and analyzes the interplay between oxidative stress, chronic inflammation and angiogenesis features. There is a special focus on recent discoveries and progress toward possible therapeutic strategies, such as the role of glucose transporters within MS; the effects of polyphenols as anti-oxidant, anti-inflammatory and anti-angiogenic compounds.

The role of NFkB, nitric oxide synthases, hypoxia-inducible factors, and many other molecules that play a part in the development of oxidative stress and inflammation as well as angiogenesis is also covered.

This book fills the gap between basic science and medical care, and provides the reader with the skills to apply rigorous basic science to clinical settings of metabolic syndrome-associated disorders.

Editors and Affiliations

  • Department of Biochemistry (U38/CFT) Faculty of Medicine, University of Porto Al. Prof. Hernani Monteiro, Portugal

    Raquel Soares

  • Department of Biochemistry (U38/CFT) Laboratory for Molecular Cell Biology Faculty of Medicine, University of Porto Al. Prof. Hernani Monteiro, Portugal

    Carla Costa

Bibliographic Information

  • Book Title: Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome

  • Editors: Raquel Soares, Carla Costa

  • DOI: https://doi.org/10.1007/978-1-4020-9701-0

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2009

  • Hardcover ISBN: 978-1-4020-9700-3Published: 12 March 2009

  • Softcover ISBN: 978-90-481-8187-2Published: 19 October 2010

  • eBook ISBN: 978-1-4020-9701-0Published: 25 February 2009

  • Edition Number: 1

  • Number of Pages: X, 210

  • Topics: Cancer Research, Oncology, Metabolic Diseases, Oxidative Stress, Diabetes

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access