Concepts and emergent therapeutic interventions
Oxidative stress molecules in metabolic syndrome
Evidence of Inflammatory pathways in metabolic syndrome
Neovascular pathways in metabolic syndrome
Cross-talk between the three processes in metabolic syndrome
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Table of contents (9 chapters)
About this book
Metabolic Syndrome (MS) is a highly prevalent condition in developed countries and is a cluster of several risk factors for type 2 diabetes and cardiovascular disease that includes increased body mass index/waist circumference, visceral obesity, insulin resistance, hyperclycaemia, dyslipidaemia and hypertension, which are all major causes of morbidity and death.
This volume provides a critical review and discussion of the knowledge gathered on MS and analyzes the interplay between oxidative stress, chronic inflammation and angiogenesis features. There is a special focus on recent discoveries and progress toward possible therapeutic strategies, such as the role of glucose transporters within MS; the effects of polyphenols as anti-oxidant, anti-inflammatory and anti-angiogenic compounds.
The role of NFkB, nitric oxide synthases, hypoxia-inducible factors, and many other molecules that play a part in the development of oxidative stress and inflammation as well as angiogenesis is also covered.
This book fills the gap between basic science and medical care, and provides the reader with the skills to apply rigorous basic science to clinical settings of metabolic syndrome-associated disorders.
Editors and Affiliations
Department of Biochemistry (U38/CFT) Faculty of Medicine, University of Porto Al. Prof. Hernani Monteiro, Portugal
Department of Biochemistry (U38/CFT) Laboratory for Molecular Cell Biology Faculty of Medicine, University of Porto Al. Prof. Hernani Monteiro, Portugal
Book Title: Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome
Editors: Raquel Soares, Carla Costa
Publisher: Springer Dordrecht
Copyright Information: Springer Science+Business Media B.V. 2009
Hardcover ISBN: 978-1-4020-9700-3Published: 12 March 2009
Softcover ISBN: 978-90-481-8187-2Published: 19 October 2010
eBook ISBN: 978-1-4020-9701-0Published: 25 February 2009
Edition Number: 1
Number of Pages: X, 210