Ecdysone: Structures and Functions

  • Guy Smagghe

Table of contents

  1. Front Matter
    Pages i-xlii
  2. Fundamental Aspects of Ecdysteroid Research: The Distribution and Diversity of Ecdysteroids in Animals and Plants

    1. Laurence Dinan, Juraj Harmatha, Vladimir Volodin, René Lafont
      Pages 3-45
    2. René Lafont, Jan Koolman
      Pages 47-71
    3. Penny M. Hopkins
      Pages 73-97
    4. Josep Coll Toledano
      Pages 99-123
  3. In the Post-Genomic Era, Ecdysteroid Genetic Hierarchies in Insect Growth and Reproduction

    1. Nadia Monesi, Juliana Aparecida Candido-Silva, Maria Luísa Paçó-Larson, Jorge Cury de Almeida
      Pages 165-183
    2. David Siaussat, Patrick Porcheron, Stephane Debernard
      Pages 185-204
    3. Garry N. Hannan, Ronald J. Hill, Skarlatos G. Dedos, Luc Swevers, Kostas Iatrou, Anjiang Tan et al.
      Pages 205-227
  4. Role of Cross Talk of Genes and Growth Factors in Ecdysteroid Titers and Signalling

  5. Ecdysteroids Function Through Nuclear and Membrane Receptors

    1. Isabelle M. L. Billas, Christopher Browning, Michael C. Lawrence, Lloyd D. Graham, Dino Moras, Ronald J. Hill
      Pages 335-360
    2. Vincent C. Henrich, Joshua Beatty, Heike Ruff, Jenna Callender, Marco Grebe, Margarethe Spindler-Barth
      Pages 361-375
    3. Anca Azoitei, Heike Ruff, Christian Tremmel, Simone Braun, Margarethe Spindler-Barth
      Pages 377-388
    4. Klaus-Dieter Spindler, Katarzyna Betanńska, Claudia Nieva, Tomasz Gwóźoanna, Joanna Dutko-Gwóźdź, Andrzej Ożyhar et al.
      Pages 389-409
  6. Ecdysteroids in Modern Agriculture, Medicine, Doping and Ecotoxicology

    1. Lloyd D. Graham, Wynona M. Johnson, Donya Tohidi-Esfahani, Anna Pawlak-Skrzecz, Marianne Bliese, George O. Lovrecz et al.
      Pages 447-474
    2. Yoshiaki Nakagawa, Robert E. Hormann, Guy Smagghe
      Pages 475-509
    3. Venkata S. Tavva, Randy D. Dinkins, Glenn B. Collins, Subba R. Palli
      Pages 511-538
    4. Thomas Soin, Tim Verslycke, Colin Janssen, Guy Smagghe
      Pages 539-549
    5. René Lafont, Laurence Dinan
      Pages 551-578
  7. Back Matter
    Pages 579-583

About this book


Ecdysone is the steroidal prohormone of the major insect moulting hormone 20-hydroxyecdysone. It groups with its homologues the steroidal molting hormones in arthropods, but they also occur in other phyla where they can play different roles. Besides ecdysteroids appear in many plants mostly as protection agents (toxins or antifeedants) against herbivorous insects.

The important developments and achievements in modern ecdysone science since the first edition in 1989 by J. Koolman have led to this new revised, expanded and retitled reference work. New chapters in this edition include RNA interference, the ecdysone receptor crystal structures and structure activity relationships, etc. Each article may also be read independently, as a review of that particular subject.

Complete up-to-date coverage of many important topics - the book is divisible into five conceptual areas: (1) Distribution and diversity of ecdysteroids in the two kingdoms is still basis, (2) In the post-genomic era, ecdysteroid genetic hierarchies in insect growth and reproduction, (3) Role of cross talk of genes and growth factors in ecdysteroid titers and signaling, (4) Ecdysteroids function through nuclear and membrane receptors, and (5) Ecdysteroids in modern agriculture, medicine, doping and ecotoxicology. Each of the 23 chapters is written by scientists active in the reviewed research area and a truly distinguished international team of contributors has been chosen.

Ecdysone, Structures and Functions will be of immense use and contains essential information for scientists, students, and professionals alike in entomology, endocrinology, physiology, chemistry, and agricultural, plant, biomedicine and environmental sciences.


DNA Ecdysone receptor, nuclear receptors Ecdysone, Steroid hormones Insects, Arthropods Metamorphosis, moulting, reproduction RNA entomology insect physiology

Editors and affiliations

  • Guy Smagghe
    • 1
  1. 1.Laboratory of Agrozoology Faculty of Bioscience EngineeringGhent UniversityBelgium

Bibliographic information