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Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders

Novel Strategies for Research and Treatment

  • Book
  • © 2008

Overview

Editors:
  1. Michael S. Ritsner

    1. Sha'ar Menashe Mental Health Center, Israel

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    You can also search for this editor in PubMed   Google Scholar

  2. Abraham Weizman

    1. Geha Mental Health Center, Israel

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    You can also search for this editor in PubMed   Google Scholar

  • Relevance of neurosteroids to neuropsychiatric disorders
  • The multi-functional position of neurosteroids in the nervous system
  • Neurosteroids as pharmacological agents
  • The role of neurosteroids in brain development, neurodegeneration and neuroplasticity
  • The cellular and molecular mechanisms involved in the activity of neurosteroids in the brain

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Table of contents (26 chapters)

  1. Neuroactive Steroids and Neuropsychiatric Disorders

    1. Neuroactive Steroids in Brain and Relevance to Mood

      • Torbjörn Bückström, Lotta Andréen, Marie Bixo, Inger Björn, Guillén Fernández, Inga-Maj Johansson et al.
      Pages 423-433

    2. The Role of Neuroactive Steroids in Anxiety Disorders

      • Erin M. MacKenzie, Glen B. Baker, Jean-Michel Le Mellédo
      Pages 435-447

    3. The Role of Midbrain 3α,5α-THP in Mediating Exploration, Anxiety, Social, and Reproductive Behavior

      • Cheryl A. Frye, Madeline E. Rhodes
      Pages 449-482

    4. The Role of Progesterone and its Metabolites in Premenstrual Disorders of Affect

      • Akiko Dohi, Glenn H. Dillon, Meharvan Singh
      Pages 483-491

    5. Neurosteroid Derangement in Women Diagnosed with Eating Disorders

      • Daniel Stein, Rachel Maayan, Ron Loewenthal, Abraham Weizman
      Pages 493-507

    6. Neurosteroids in Alcohol and Substance Use

      • Brett C. Ginsburg, Lisa R. Gerak, Lance R. McMahon, John D. Roache
      Pages 509-538

    7. The Role of Neurosteroids in Development of Pediatric Psychopathology

      • Pavel Golubchik, Abraham Weizman
      Pages 539-553

  2. Back Matter

    Pages 555-559
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Keywords

About this book

Over the past few decades the involvement of neurosteroids in brain function and mental health has attracted much interest, not only from a neuroscience perspective, but also from clinical and therapeutic aspects. In recent years, much of the research has focused on the multifunctional position of neurosteroids in the nervous system. The areas that have been explored, in particular, are the cellular and molecular mechanisms involved in the activity of neurosteroids in the brain, the role of neurosteroids in brain development, neurodegeneration and neuroplasticity, and their pharmacological properties. The large increase in the number of publications highlights this amplified interest in neurosteroids. Over the last 7 years at least 400 papers have been published describing the putative role of neurosteroids in the modulation of basic brain function and in the etiology and treatment of psychiatric and neurological disorders. Contributors to this book are amongst the most active basic researchers and c- nicians in the field and provide new perspectives not only clarifying some of the ongoing controversies, but also proposing diverse aspects and new insights. The book is organized in two major sections: “Neuroactive steroids and brain function’, and ‘Neuroactive steroids and neuropsychiatric disorders”. Though the selection of topics has been influenced by the current state of the art and the issues that require further elaboration, one should not assume that these are the only significant issues at this time.

Reviews

From the reviews:

"This is a first rate book on an exciting area: steroids and the brain. … Written and edited by active researchers involved in this area of study, this book is a must for anyone interested in keeping abreast of this exploding field. … The targeted audience includes clinicians, researchers, and students. … This is an excellent, comprehensive book covering an important and emerging area of neuropsychiatric research. Anyone wishing to stay up to date on neurosteroids would benefit from reading it." (Michael J. Schrift, Doody’s Review Service, July, 2008)

"Neuroactive Steroids in Brain Function, Behavior, and Neuropsychiatric Disorders: Novel Strategies for Research and Treatment provides reviews on neurosteroid mechanisms of action, their role in brain function, and their probable therapeutic as well as contributory roles to neurodegenerative and psychiatric disorders. … is recommended for researchers interested in neurosteroids but also for clinicians who are able to devote enough time and attention to the material." (Catherine C. Price, PsycCRITIQUES, Vol. 53 (51), December, 2008)

Editors and Affiliations

  • Sha'ar Menashe Mental Health Center, Israel

    Michael S. Ritsner

  • Geha Mental Health Center, Israel

    Abraham Weizman

Bibliographic Information

  • Book Title: Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders

  • Book Subtitle: Novel Strategies for Research and Treatment

  • Editors: Michael S. Ritsner, Abraham Weizman

  • DOI: https://doi.org/10.1007/978-1-4020-6854-6

  • Publisher: Springer Dordrecht

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2008

  • Hardcover ISBN: 978-1-4020-6853-9Published: 18 February 2008

  • Softcover ISBN: 978-90-481-7738-7Published: 19 October 2010

  • eBook ISBN: 978-1-4020-6854-6Published: 01 February 2008

  • Edition Number: 1

  • Number of Pages: XX, 564

  • Number of Illustrations: 50 b/w illustrations

  • Topics: Neurology, Endocrinology, Neurosciences, Psychiatry, Biological Psychology, Laboratory Medicine

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