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  • © 2007

Genes, Development and Cancer

The Life and Work of Edward B. Lewis

  • For the first time, Nobel Prize winner, Edward B. Lewis' research papers are published within one volume

  • Papers are organized into sections that reflect the focus of the research

  • Commentaries by Howard Lipshitz highlight key methods and results by explaining the science so it is accessible to upper-level undergraduates, graduate students, and professional researchers

  • Provides source material for advanced undergraduate and graduate level courses in genetics, developmental biology, radiation and cancer

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-xlvi
  2. Genes and Development

    1. Front Matter

      Pages 178-198
    2. Genes and Developmental Pathways

      • E. B. Lewis
      Pages 199-228
  3. Molecules and Development

    1. Front Matter

      Pages 298-310
    2. Molecular Genetics of the Bithorax Complex in Drosophila Melanogaster

      • Welcome Bender, Michael Akam, François Karch, Philip A. Beachy, Mark Peifer, Pierre Spierer et al.
      Pages 311-326
    3. The Abdominal Region of the Bithorax Complex

      • François Karch, Barbara Weiffenbach, Mark Peifer, Welcome Bender, Ian Duncan, Susan Celniker et al.
      Pages 327-357

About this book

Edward B. Lewis' science is the bridge linking experimental genetics as conducted in the first half of the twentieth century, and the powerful molecular genetic approaches that revolutionized the field in its last quarter. His Nobel Prize winning studies founded the field of developmental genetics and laid the groundwork for our current understanding of the universal, evolutionarily conserved strategies controlling animal development. A lesser-known aspect of Lewis' canon is the pioneering studies he carried out on ionizing radiation and human cancer. In doing so, he was propelled into a public storm over nuclear weapons testing policy. For the first time Lewis' key publications in the fields of genetics, developmental biology, radiation and cancer are compiled within one volume.

The Second Edition has been expanded with new material and the commentaries have been updated.

Reviews

“A great book that is of interest to many geneticists, developmental biologists, and historians of science.” (Prof. Matthew P. Scott - Stanford University)

“A wonderful compendium of Lewis' papers. Lipshitz has done an outstanding job of summarizing – and in many cases clarifying – Lewis' writings.” (Prof. James F. Crow, University of Wisconsin, Madison)

“A very valuable reference for those studying developmental biology, radiation and cancer.” (Dr. Susan Celniker, Lawrence Berkeley National Laboratory, Berkeley, California)

“An excellent resource for understanding the emergence of developmental genetics.” (Prof. Siegfried Roth, University of Köln, Germany)

“Since the best way to become a good scientist is to understand how scientific ideas have been born and have developed, this book should be read by all graduate students in the areas of genetics, development and evolution.” (Prof. Markus Noll, University of Zurich, Switzerland)

Editors and Affiliations

  • Department of Medical Genetics and Microbiology Graduate Department of Molecular and Medical Genetics Canada Research Chair in Developmental Biology, University of Toronto, Toronto, Canada

    Howard D. Lipshitz

  • Program in Developmental and Stem Cell Biology, Hospital for Sick Children Research Institute, Toronto, Canada

    Howard D. Lipshitz

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (Canada)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (Canada)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access