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Table of contents

  1. Front Matter
    Pages i-xii
  2. Jack S. Cohen
    Pages 1-6
  3. Paul S. Miller
    Pages 79-95
  4. C. A. Stein, Jack S. Cohen
    Pages 97-117
  5. B. Rayner, C. Malvy, J. Paoletti, B. Lebleu, C. Paoletti, J.-L. Imbach
    Pages 119-136
  6. D. G. Knorre, V. V. Vlassov, V. F. Zarytova
    Pages 173-196
  7. Gerald Zon
    Pages 233-247
  8. Back Matter
    Pages 249-255

About this book

Introduction

This first-ever book on oligodeoxynucleotides describes in detail the new antisense approach to chemotherapy. It is written by world experts, covers all areas of current knowledge and includes new results. The principle of the antisense approach is that an antisense mRNA base sequence will bind to its target mRNA base sequence and thus bring about the selective inhibition of gene expression. The antisense approach is important in general in understanding gene function, and more specifically as a potential basis for new drugs, notably against cancer and viral genes.

Keywords

cancer cell DNA gene gene expression genes nucleic acid nucleotide

Editors and affiliations

  • Jack S. Cohen
    • 1
  1. 1.National Cancer InstituteNational Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-349-10869-5
  • Copyright Information Macmillan Publishers Limited 1989
  • Publisher Name Palgrave, London
  • eBook Packages Engineering
  • Print ISBN 978-1-349-10871-8
  • Online ISBN 978-1-349-10869-5
  • Buy this book on publisher's site