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Characterization of Nanoparticles Intended for Drug Delivery

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  • © 2024
  • Latest edition

Overview

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 2789)

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About this book

This third edition volume expands on the previous editions with new and updated discussions on the latest developments in endotoxin contamination, complex physicochemical properties, in vitro immunotoxicity traits, and in vitro drug release properties. Eight chapters in this book are dedicated to physicochemical characterization techniques and cover newer methods such as asymmetric-flow field-flow fractionation, single particle inductively coupled plasma mass spectrometry, and resistive pulse sensing. The next eighteen chapters explore the immunotoxicity of nanomaterials, including microbial contaminants such as endotoxin and beta-glucans, anti-PEG antibodies, autoimmunity, and immunosuppressive properties. The last two chapters talk about new pharmacology protocols, including a new technique to assess drug release and a tissue distribution assay using PEG immunohistochemistry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step instructions to reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Cutting-edge and thorough, Characterization of Nanoparticles Intended for Drug Delivery, Third Edition is a valuable resource that will help both expert and novice researchers further enhance their understanding of this important and developing field.


Keywords

Table of contents (28 protocols)

  1. Introduction

  2. Immunotoxicity

Editors and Affiliations

  • Nanotechnology Characterization Laboratory Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, USA

    Jeffrey D. Clogston, Rachael M. Crist, Marina A. Dobrovolskaia, Stephan T. Stern

Bibliographic Information

  • Book Title: Characterization of Nanoparticles Intended for Drug Delivery

  • Editors: Jeffrey D. Clogston, Rachael M. Crist, Marina A. Dobrovolskaia, Stephan T. Stern

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-0716-3786-9

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Leidos Biomedical Research Inc. 2024

  • Hardcover ISBN: 978-1-0716-3785-2Published: 21 March 2024

  • Softcover ISBN: 978-1-0716-3788-3Due: 04 April 2025

  • eBook ISBN: 978-1-0716-3786-9Published: 20 March 2024

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 3

  • Number of Pages: XII, 324

  • Number of Illustrations: 1 b/w illustrations

  • Topics: Pharmacology/Toxicology, Nanotechnology, Biomedicine, general

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