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  • © 2023

Metagenomic Data Analysis

Editors:

  • Includes cutting-edge methods and protocols

  • Provides step-by-step detail essential for reproducible results

  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 2649)

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Table of contents (20 protocols)

  1. Front Matter

    Pages i-xiii
  2. Quality Control in Metagenomics Data

    • Abraham Gihawi, Ryan Cardenas, Rachel Hurst, Daniel S. Brewer
    Pages 21-54
  3. Metagenomics Databases for Bacteria

    • Dapeng Wang
    Pages 55-67
  4. DIAMOND +  MEGAN Microbiome Analysis

    • Anupam Gautam, Wenhuan Zeng, Daniel H. Huson
    Pages 107-131
  5. Interactive Web-Based Services for Metagenomic Data Analysis and Comparisons

    • Nehal Adel Abdelsalam, Hajar Elshora, Mohamed El-Hadidi
    Pages 133-174
  6. Application of High-Throughput Sequencing (HTS) to Enhance the Well-Being of an Endangered Species (Malayan Tapir): Characterization of Gut Microbiome Using MG-RAST

    • Ramitha Arumugam, Prithivan Ravichandran, Swee Keong Yeap, Reuben Sunil Kumar Sharma, Shahrizim Bin Zulkifly, Donny Yawah et al.
    Pages 175-194
  7. Nanopore Sequencing Techniques: A Comparison of the MinKNOW and the Alignator Sequencers

    • Sebastian Oeck, Alicia I. Tüns, Alexander Schramm
    Pages 209-221
  8. MAIRA: Protein-based Analysis of MinION Reads on a Laptop

    • Caner Bağcı, Benjamin Albrecht, Daniel H. Huson
    Pages 223-234
  9. Recovery and Analysis of Long-Read Metagenome-Assembled Genomes

    • Krithika Arumugam, Irina Bessarab, Mindia A. S. Haryono, Rohan B. H. Williams
    Pages 235-259
  10. Tracking Antibiotic Resistance from the Environment to Human Health

    • Eman Abdelrazik, Mohamed El-Hadidi
    Pages 289-301
  11. Assembly and Annotation of Viral Metagenomes from Short-Read Sequencing Data

    • Mihnea R. Mangalea, Kristopher Keift, Breck A. Duerkop, Karthik Anantharaman
    Pages 317-337
  12. Metagenomics Data Visualization Using R

    • Alex Coleman, Anupam Bose, Suparna Mitra
    Pages 359-392

About this book

This volume describes different sequencing methods, pipelines and tools for metagenome data analyses. Chapters guide readers through quality control of raw sequence data, metagenomics databases for bacterial annotations such Greengenes, SILVA, RDP and GTDB, guide to 16S rRNA microbiome analysis and pipelines such as mothur, DADA2, QIIME2 , whole genome shotgun metagenomics data analyses pipeline using MEGAN and DIAMOND, web service such as PATRIC, RDP, mothur, Kaiju, PhyloPythiaS, MG-RAST, WebMGA, MicrobiomeAnalyst, WHAM!, METAGENassist and MGnify: EBI-Metagenomics, MG-RAST Metagenomics Analysis. Then the chapters inform the readers regarding Third-generation sequencing (TGS) approaches as MinION sequencing and teaches use of Ubuntu Linux Virtual Machine configuration, clinical and environmental resistomes, use of FISH techniques and designing FISH probes, protocols for viral metagenomics, and comprehensive guideline for microbiome analysis using most used R packages. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

 

Authoritative and cutting-edge, Metagenomic Data Analysis: Methods and Protocols aims to be comprehensive guide for researchers to specialize in the metagenomics field.

 

Keywords

  • Sequencing
  • microbial ecosystem
  • MinION sequencing
  • Next-Generation Sequencing
  • shotgun metagenomics

Editors and Affiliations

  • Leeds Institute of Medical Research, University of Leeds, Leeds, UK

    Suparna Mitra

Bibliographic Information

  • Book Title: Metagenomic Data Analysis

  • Editors: Suparna Mitra

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-0716-3072-3

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2023

  • Hardcover ISBN: 978-1-0716-3071-6Published: 02 June 2023

  • Softcover ISBN: 978-1-0716-3074-7Due: 16 June 2024

  • eBook ISBN: 978-1-0716-3072-3Published: 31 May 2023

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XIII, 441

  • Number of Illustrations: 12 b/w illustrations, 168 illustrations in colour

  • Topics: Genetics and Genomics, Microbial Genetics and Genomics

Buy it now

Buying options

eBook GBP 143.50
Price includes VAT (United Kingdom)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book GBP 179.99
Price includes VAT (United Kingdom)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access