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Translational Research Methods for Major Depressive Disorder

  • Book
  • © 2022

Overview

Editors:
  1. Yong-Ku Kim

    1. Department of Psychiatry, Korea University Ansan Hospital, Ansan, Korea (Republic of)

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    You can also search for this editor in PubMed   Google Scholar

  2. Meysam Amidfar

    1. Deptartment of Speech Therapy, Isfahan University of Medical Sciences, Isfahan, Iran

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 179)

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Table of contents (20 protocols)

  1. Front Matter

    Pages i-xviii
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  3. Behavioral Research Methods for Major Depression

    1. Front Matter

      Pages 85-85
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    2. Translational Strategies for Developing Biomarkers for Major Depression: Lessons Learned from Animal Models

      • Feyza Aricioglu, Brian E. Leonard
      Pages 87-121

    3. Animal Model Approaches to Understanding the Neurobiology of Suicidal Behavior

      • Raquel Romay-Tallon, Graziano Pinna
      Pages 123-145

    4. Behavioral Paradigms for Assessing Cognitive Functions in the Chronic Social Defeat Stress Model of Depression

      • Marc Fakhoury, Michael Fritz, Sama F. Sleiman
      Pages 147-164

  4. Cellular and Molecular Research Methods for Major Depression

    1. Front Matter

      Pages 165-165
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    2. Optogenetic Animal Models of Depression: From Mice to Men

      • Ayla Arslan, Pinar Unal-Aydin, Taner Dogan, Orkun Aydin
      Pages 167-191

    3. The Effects of Antidepressants on Neurotransmission: Translational Insights from In Vivo Electrophysiological Studies

      • Meysam Amidfar, Yong-Ku Kim
      Pages 193-205

    4. The Role of Transcriptional Profiling in Neurobiology and Treatment of Major Depression: A Translational Perspective on RNA Sequencing Platform

      • Bhaskar Roy, Praveen Korla, Yogesh Dwivedi
      Pages 207-224

  5. Neuroimaging Research Methods for Major Depression

    1. Front Matter

      Pages 225-225
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    2. Molecular Imaging of Major Depressive Disorder with Positron Emission Tomography: Translational Implications for Neurobiology and Treatment

      • Mikael Tiger, Johan Lundberg
      Pages 227-240

    3. Magnetic Resonance Imaging as a Translational Research Tool for Major Depression

      • Chien-Han Lai
      Pages 241-264

    4. Neurobiochemistry Alterations Associated with Major Depression: A Review of Translational Magnetic Resonance Spectroscopic Studies

      • Darren William Roddy, John R. Kelly, Thomas Drago, Kesidha Raajakesary, Madeline Haines, Erik O’Hanlon
      Pages 265-309

    5. Deficits of Neurotransmitter Systems and Altered Brain Connectivity in Major Depression: A Translational Neuroscience Perspective

      • Je-Yeon Yun, Yong-Ku Kim
      Pages 311-324

  6. Translational Interventions

    1. Front Matter

      Pages 325-325
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Keywords

About this book

This volume explores the latest techniques used to study brain function and pathophysiology of major depressive disorder (MDD), and includes suggestions of new therapeutic approaches for the treatment of MDD. The chapters into this book are organized into five parts. Part One discusses advanced approaches to studying well-established pathophysiological mechanisms. Part Two details behavioral research methods for MDD. Part Three looks at the cellular and molecular research methods for major depression, and Part Four describes the latest developments in non-invasive neuroimaging. Part Five focuses on the pharmacological and non-pharmacological interactions, including antidepressant agents and their properties, such as sexual side effects and neuroimaging biomarkers. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and comprehensive, TranslationalResearch Methods for Major Depressive Disorders is a valuable resource for researchers and scientists interested in learning more about this important and developing field. 


Editors and Affiliations

  • Department of Psychiatry, Korea University Ansan Hospital, Ansan, Korea (Republic of)

    Yong-Ku Kim

  • Deptartment of Speech Therapy, Isfahan University of Medical Sciences, Isfahan, Iran

    Meysam Amidfar

Bibliographic Information

  • Book Title: Translational Research Methods for Major Depressive Disorder

  • Editors: Yong-Ku Kim, Meysam Amidfar

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-0716-2083-0

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2022

  • Hardcover ISBN: 978-1-0716-2082-3Published: 13 February 2022

  • Softcover ISBN: 978-1-0716-2085-4Published: 13 February 2022

  • eBook ISBN: 978-1-0716-2083-0Published: 12 February 2022

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XVIII, 519

  • Number of Illustrations: 23 b/w illustrations, 31 illustrations in colour

  • Topics: Neurosciences

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