In Silico Methods for Predicting Drug Toxicity

Front Matter

PBPK Modeling to Simulate the Fate of Compounds in Living Organisms

• Frédéric Y. Bois, Cleo Tebby, Céline Brochot

Pharmacokinetic Tools and Applications

• Judith C. Madden, Courtney V. Thompson

In Silico Tools and Software to Predict ADMET of New Drug Candidates

• Supratik Kar, Kunal Roy, Jerzy Leszczynski

Front Matter

Development of In Silico Methods for Toxicity Prediction in Collaboration Between Academia and the Pharmaceutical Industry

• Manuel Pastor, Ferran Sanz, Frank Bringezu

Emerging Bioinformatics Methods and Resources in Drug Toxicology

• Karine Audouze, Olivier Taboureau

Front Matter

In Silico Prediction of Chemically Induced Mutagenicity: A Weight of Evidence Approach Integrating Information from QSAR Models and Read-Across Predictions

• Enrico Mombelli, Giuseppa Raitano, Emilio Benfenati

In Silico Methods for Chromosome Damage

• Diego Baderna, Ilse Van Overmeire, Giovanna J. Lavado, Domenico Gadaleta, Birgit Mertens

In Silico Methods for Carcinogenicity Assessment

• Azadi Golbamaki, Emilio Benfenati, Alessandra Roncaglioni

In Silico Models for Developmental Toxicity

• Marco Marzo, Alessandra Roncaglioni, Sunil Kulkarni, Tara S. Barton-Maclaren, Emilio Benfenati

In Silico Models for Repeated-Dose Toxicity (RDT): Prediction of the No Observed Adverse Effect Level (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL) for Drugs

• Fabiola Pizzo, Domenico Gadaleta, Emilio Benfenati

In Silico Models for Predicting Acute Systemic Toxicity

• Ivanka Tsakovska, Antonia Diukendjieva, Andrew P. Worth

In Silico Models for Skin Sensitization and Irritation

• Gianluca Selvestrel, Federica Robino, Matteo Zanotti Russo

In Silico Models for Hepatotoxicity

• Claire Ellison, Mark Hewitt, Katarzyna Przybylak

Machine Learning Models for Predicting Liver Toxicity

• Jie Liu, Wenjing Guo, Sugunadevi Sakkiah, Zuowei Ji, Gokhan Yavas, Wen Zou et al.

Front Matter