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Recoding: Expansion of Decoding Rules Enriches Gene Expression

  • John F. Atkins
  • Raymond F.  Gesteland

Part of the Nucleic Acids and Molecular Biology book series (NUCLEIC, volume 24)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Redefinition

    1. Front Matter
      Pages 1-1
    2. Vadim N. Gladyshev, Dolph L. Hatfield
      Pages 3-27
    3. Joseph A. Krzycki
      Pages 53-77
    4. Olivier Namy, Jean-Pierre Rousset
      Pages 79-100
    5. Jeremy D. Brown, Martin D. Ryan
      Pages 101-121
    6. Kim M. Keeling, David M. Bedwell
      Pages 123-146
  3. Frameshifting – Redirection of Linear Readout

    1. Front Matter
      Pages 147-147
    2. Ian Brierley, Robert J.C. Gilbert, Simon Pennell
      Pages 149-174
    3. W. Allen Miller, David P. Giedroc
      Pages 193-220
    4. Philip J. Farabaugh
      Pages 221-247
    5. Roger W. Hendrix
      Pages 249-258
    6. Pavel V. Baranov, Olga Gurvich
      Pages 301-320
    7. Jonathan D. Dinman, Michael O’Connor
      Pages 321-344
    8. Markus Pech, Oliver Vesper, Hiroshi Yamamoto, Daniel N. Wilson, Knud H. Nierhaus
      Pages 345-362
  4. Discontiguity

    1. Front Matter
      Pages 363-363
    2. Kenneth C. Keiler, Dennis M. Lee
      Pages 383-405
  5. Transcription Slippage

    1. Front Matter
      Pages 407-407
    2. Michael Anikin, Vadim Molodtsov, Dmitry Temiakov, William T. McAllister
      Pages 409-432
  6. Appendix

    1. Front Matter
      Pages 433-433
    2. Andrew E. Firth, Michaël Bekaert, Pavel V. Baranov
      Pages 435-461
  7. Back Matter
    Pages 463-466

About this book

Introduction

The dynamic nature of decoding the information in messenger RNA was unanticipated at the time the genetic code was first deciphered.   We now know that both the meaning of individual codons and the framing of the readout process can be modified by information in specific messenger RNAs.  This book describes this "Recoding" phenomenon, revealing the diversity of an additional layer of information in mRNAs that serves to enrich the expression of genes.  Knowledge of recoding is essential for understanding the organization and expression of genes in viruses and all organisms ranging from bacteria to archeae to plants to humans, making Recoding pertinent to all biological sciences.

Keywords

Amino acid Codons RNA Translation Viruses gene expression genes genetics microbiology mutant proteins tRNA transcription virus

Editors and affiliations

  • John F. Atkins
    • 1
  • Raymond F.  Gesteland
    • 2
  1. 1.Molecular Biology ProgramUniversity of UtahSalt Late CityU.S.A.
  2. 2.Dept. BioengineeringUniversity of UtahSalt Lake CityU.S.A.

Bibliographic information

  • DOI https://doi.org/10.1007/978-0-387-89382-2
  • Copyright Information Springer-Verlag New York 2010
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-0-387-89381-5
  • Online ISBN 978-0-387-89382-2
  • Series Print ISSN 0933-1891
  • Series Online ISSN 1869-2486
  • Buy this book on publisher's site