Clinical Nephrotoxins

Renal Injury from Drugs and Chemicals

  • Marc E. De Broe
  • George A. Porter
  • William M. Bennett
  • Gilbert Deray

Table of contents

  1. Front Matter
    Pages i-xvii
  2. General

    1. George A. Porter
      Pages 3-28
    2. Mitchell H. Rosner, Mark D. Okusa
      Pages 29-41
    3. Marc E. De Broe, FranÇoise Roch-Ramel
      Pages 43-71
    4. Marisa D. Covington, Rick G. Schnellmann
      Pages 73-83
    5. Hubert G. Leufkens, Antoine C. Egberts
      Pages 85-90
    6. William F. Finn, George A. Porter
      Pages 92-130
    7. Lucette Pelletier, Abdelhadi Saoudi, Gilbert Fournié
      Pages 131-153
    8. Istvan Arany, Gur P. Kaushal, Didier Portilla, Judit Megyesi, Peter M. Price, Robert L. Safirstein
      Pages 155-170
    9. Zoltan H. Endre, Charles L. Edelstein
      Pages 173-221
    10. Paul Jennings, Christian KoppelstÄtter, Judith Lechner, Walter Pfaller
      Pages 223-249
    11. James F. Winchester, Nikolas Harbord, Donald A. Feinfeld
      Pages 251-264
  3. Specific Drugs

    1. Brian S. Decker, Bruce A. Molitoris
      Pages 267-292
    2. Constantin Cojocel
      Pages 293-321
    3. Nathalie K. Zgheib, Blair Capitano, Robert A. Branch
      Pages 323-352
    4. Gabriel N. Contreras, Cristiane Mocelin Carvalho, Jorge M. Diego, Decio Carvalho, Isabel Espinal
      Pages 353-381
    5. Jeffrey S. Berns, Alden Doyle, Nishaminy Kasbekar
      Pages 383-398
    6. Monique M. Elseviers, Marc E. De Broe
      Pages 399-417
    7. Ali J. Olyaei, Andrew Whelton, Til Sturmer, George A. Porter
      Pages 419-457
    8. Shiro Ueda, George A. Porter
      Pages 459-479

About this book


Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals is a comprehensive handbook on all aspects of adverse effects by drugs and chemical substances on the kidneys. The importance of the toxicity of drugs and other substances for the kidneys is increasingly recognized.

The first, general part deals with themes as clinical relevance, renal handling, pharmacovigilance, urinary biomarkers, pharmacological, immunological and cellular aspects of nephrotoxicity, as well as animal and cell culture models. The second part includes the specific drugs; the third part gives the description of environmental and occupational nephrotoxins. The last part deals with the patient with some degree of renal failure, exposed to drugs and chemicals, the progression of renal disease, and how to adapt drug dosage.

In this third and completely revised edition, nine new chapters were added, from proton pump inhibitors to bisphosphonates, phosphate containing laxatives, oxalate, star fruit and smoking. All chapters were extended with up-to-date references.

The book is of interest for the nephrologist, internist, general practitioner, toxicologist, pharmacologist, anesthesiologist, epidemiologist, public health official, pharmaceutical industry, and national drug safety committees, among others.


Internist antibiotic intensive care interferon kidney nephrotoxins, renal injury, drugs, urinary biomarkers prevention

Editors and affiliations

  • Marc E. De Broe
    • 1
  • George A. Porter
    • 2
  • William M. Bennett
    • 3
  • Gilbert Deray
    • 4
  1. 1.Laboratory of Pathophysiology Universiteitsplein 1University of AntwerpWilrijkBelgium
  2. 2.Division of Nephrology, Hypertension and Clinical PharmacologyOregon Health Sciences UniversityPortlandUSA
  3. 3.Legacy Good Samaritan HospitalPortlandUSA
  4. 4.Groupe Hôspitalier Pitié Salpétrière Service De Néphrologie 83Boulevard de l′HôpitalParisFrance

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 2008
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine
  • Print ISBN 978-0-387-84842-6
  • Online ISBN 978-0-387-84843-3
  • About this book