Transgenesis and the Management of Vector-Borne Disease

  • Serap Aksoy

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 627)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. David A. O’Brochta, Alfred M. Handler
    Pages 1-18
  3. Brian D. Foy, Ken E. Olson
    Pages 19-34
  4. Serap Aksoy, Brian Weiss, Geoffrey Attardo
    Pages 35-48
  5. Guido Favia, Irene Ricci, Massimo Marzorati, Ilaria Negri, Alberto Alma, Luciano Sacchi et al.
    Pages 49-59
  6. William C. Black IV, Norma Gorrochetegui-Escalante, Nadine P. Randle, Martin J. Donnelly
    Pages 71-83
  7. Mark Q. Benedict, Alan S. Robinson
    Pages 84-92
  8. Luke Alphey, Derric Nimmo, Sinead O’Connell, Nina Alphey
    Pages 93-103
  9. Peter E. Cook, Conor J. McMeniman, Scott L. O’Neill
    Pages 126-140
  10. Thomas A. Miller, Carol R. Lauzon, David J. Lampe
    Pages 141-150
  11. Thomas W. Scott, Laura C. Harrington, Bart G. J. Knols, Willem Takken
    Pages 151-168
  12. Back Matter
    Pages 169-171

About this book

Introduction

Parasitic, bacterial and viral agents continue to challenge the welfare of humans, livestock, wild life and plants worldwide. The public health impact and financial consequences of these diseases are particularly hard on the already overburdened economies of developing countries especially in the tropics. Many of these disease agents utilize insect hosts (vectors) to achieve their transmission to mammals. In the past, these diseases were largely controlled by insecticide-based vector reduction strategies. Now, many of these diseases have reemerged in the tropics, recolonizing their previous range, and expanding into new territories previously not considered to be endemic. Habitat change, irrigation practices, atmospheric and climate change, insecticide and drug resistance as well as increases in global tourism, human traffic and commercial activities, have driven the reemergence and spread of vector borne diseases. While these diseases can be controlled through interventions aimed at both their vertebrate and invertebrate hosts, no effective vaccines exist, and only limited therapeutic prospects are available for their control in mammalian hosts. Molecular technologies such as transgenesis, which is the subject of this book, stand to increase the toolbox and benefit disease management strategies.

Keywords

Prevention Public Health biotechnology disease management disease prevention induction vaccine

Editors and affiliations

  • Serap Aksoy
    • 1
  1. 1.Division of Epidemiology and Microbial DiseasesYale University School of Public HealthNew HavenUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-0-387-78225-6
  • Copyright Information Landes Bioscience and Springer Science+Business Media, LLC 2008
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-0-387-78224-9
  • Online ISBN 978-0-387-78225-6
  • Series Print ISSN 0065-2598
  • About this book