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Acinetobacter Biology and Pathogenesis

  • Mauro Bendinelli
  • Herman Friedman
  • Eugénie Bergogne-Bérézin

Part of the Infectious Agents and Pathogenesis book series (IAPA)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Eugénie Bergogne-Bérézin
    Pages 1-18
  3. L. Nicholas Ornston, Donna Parke
    Pages 47-60
  4. Hilmar Wisplinghoff, Harald Seifert
    Pages 61-83
  5. Thamarai Schneiders, Jacqueline Findlay, Sebastian G.B. Amyes
    Pages 105-127
  6. Laurent Poirel, Patrice Nordmann
    Pages 129-143
  7. Grziela Braun
    Pages 145-154
  8. Marie Laure Joly-Guillou, Michel Wolff
    Pages 167-174
  9. Jordi Vila, Jerónimo Pachón
    Pages 175-196
  10. Clinton Murray, Paul T. Scott, Kim A. Moran, David W. Craft
    Pages 197-209
  11. Eugénie Bergogne-Bérézin
    Pages 211-216
  12. Back Matter
    Pages 217-220

About this book

Introduction

There is currently increasing interest concerning the biology and disease caused by Acinetobacter species. Such interest, however, developed relatively slowly because of the necessity to clarify the confusing taxonomy of these organisms. Much work was needed to identify various species as members of this genus, to recognize their epidemiologic profile, their pathogenic role and their increasing importance as multi-antibiotic resistant organisms. In recent years improvement of genetic approaches, recognition of plasmids, integrons and chromosomal sources of resistance mechanisms aroused interest on the role of Acinetobacters in disease by many microbiologists and clinicians, especially internists and infectious disease specialists. In this regard, physicians are frequently confronted with extremely difficult therapeutic approaches for treatment and prevention of severe nosocomial infections due to multi antibiotic resistant Acinetobacter. Moreover, recent observations of community acquired infections have been reported, especially in patients with various risk factors such as immuno-deficiencies. Also, it is now becoming evident that Acinetobacter infections occur frequently in violent situations such as earthquake or war zones.

The mechanisms of Acinetobacter virulence are becoming increasingly clear, providing new insights into their pathogenic role in community acquired infections. It is apparent the time is appropriate for detailed review of the increasing knowledge concerning important new information, both clinical and therapeutic, especially information concerning virulence, resistance mechanisms and typing of Acinetobacter spp. Many new findings are accumulating in almost an exponential manner since publication of previous books on this subject in 1991 and 1996.

Keywords

Internist antibiotic antibiotics gene gene expression infection infections infectious disease pathogenesis prevention resistance taxonomy

Editors and affiliations

  • Mauro Bendinelli
  • Herman Friedman
  • Eugénie Bergogne-Bérézin

There are no affiliations available

Bibliographic information