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Molecular Mechanisms of Exocytosis

  • Romano Regazzi

Part of the Molecular Biology Intelligence Unit book series (MBIU)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Emmanuel Sotirakis, Thierry Galli
    Pages 1-9
  3. Alexander J. A. Groffen, Matthijs Verhage
    Pages 10-27
  4. Pietro Baldelli, Anna Fassio, Anna Corradi, Flavia Valtorta, Fabio Benfenati
    Pages 62-74
  5. Marie-France Bader, Nicolas Vitale
    Pages 75-83
  6. Christine Salaün, Luke H. Chamberlain
    Pages 84-99
  7. Cristiana Brochetta, Ulrich Blank
    Pages 100-116
  8. Claudia Nora Tomes
    Pages 117-147
  9. Emanuele Cocucci, Jacopo Meldolesi
    Pages 148-160
  10. Back Matter
    Pages 175-178

About this book

Introduction

Exocytosis is a fundamental cellular process that is used by eukaryotic cells to release a variety of biological compounds including peptide hormones and neurotransmitters or to insert specific lipids and proteins in the plasma membrane. In recent years, a multidisciplinary approach promoted an extraordinary progress in the understanding of the molecular mechanisms regulating exocytosis. This led to the discovery of a large number of components belonging to the machinery that governs the fusion of secretory vesicles with plasma membranes in different cell systems, including neuronal and endocrine cells. The basic machinery required for vesicle fusion turned out to be well conserved through evolution from yeast to man. So far, because of the large number of components involved, understanding of the molecular basis of exocytosis has remained the privilege of a relatively small group of specialists. This book, written by recognized experts in the field aims at clarifying for a non-specialist audience the role of the key players in the exocytotic process not only in neuronal and endocrine cells but also in a variety of other relevant cell systems. The book represents a unique collection of up-to-date reviews that will introduce researchers and students to the forefront of this rapidly moving and fascinating field.

Keywords

cell enzyme enzymes evolution membrane molecular mechanisms neurotransmitter protein proteins regulation

Authors and affiliations

  • Romano Regazzi
    • 1
  1. 1.Department of Cell Biology and MorphologyUniversity of LausanneLausanneSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-0-387-39961-4
  • Copyright Information Landes Bioscience and Springer Science+Business Media, LLC 2007
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-0-387-39960-7
  • Online ISBN 978-0-387-39961-4
  • Buy this book on publisher's site