Hepatitis Delta Virus

  • John L. Casey

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 307)

Table of contents

  1. Front Matter
    Pages I-IX
  2. T. B. Macnaughton, M. M. C. Lai
    Pages 25-45
  3. M. D. Been
    Pages 47-65
  4. J. L. Casey
    Pages 67-89
  5. W. -H. Huang, C. -W. Chen, H. -L. Wu, P. -J. Chen
    Pages 91-112
  6. M. Fiedler, M. Roggendorf
    Pages 187-209
  7. J. L. Casey, J. L. Gerin
    Pages 211-225
  8. Back Matter
    Pages 226-230

About this book

Introduction

Since its discovery nearly 30 years ago, hepatitis delta virus (HDV) has continued to surprise and fascinate. At 1,680 nucleotides the HDV genome is the smallest known to infect man. It is unique among animal viruses, the closest known relatives being plant viroids. To compensate for its limited protein coding capacity, HDV relies heavily on host functions and on structural features of its circular RNA genome. HDV infection depends on hepatitis B virus as a helper, and increases the severity of liver disease caused by HBV alone. There is currently neither an effective HDV vaccine nor a generally accepted useful therapy for HDV infection. This volume encompasses recent developments in HDV research, from molecular virology to genetics to experimental investigation of new therapeutic and vaccine candidates.

Keywords

Antigen RNA antibody genetics hepatitis hepatitis B immunology infection liver liver disease protein proteins ribozyme virology virus

Editors and affiliations

  • John L. Casey
    • 1
  1. 1.Department of Microbiology and ImmunologyGeorgetown UniversityWashington, DCUSA

Bibliographic information

  • DOI https://doi.org/10.1007/3-540-29802-9
  • Copyright Information Springer-Verlag Berlin Heidelberg 2006
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-29801-4
  • Online ISBN 978-3-540-29802-1
  • Series Print ISSN 0070-217X
  • About this book