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Homing Endonucleases and Inteins

  • Book
  • © 2005


  • First book devoted exclusively to the biology and technical applications growing out of research with inteins and homing endonucleases
  • Includes supplementary material:

Part of the book series: Nucleic Acids and Molecular Biology (NUCLEIC, volume 16)

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About this book

This book provides the first and only comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies, which are tied together through their frequent fusion and coevolution, have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations.

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Table of contents (20 chapters)

Editors and Affiliations

  • Wadsworth Center/NYSDOH, Center for Medical Science, Albany, USA

    Marlene Belfort, Victoria Derbyshire

  • Dept. of Chemical Engineering, Princeton University, Princeton, USA

    David W. Wood

  • Fred Hutchinson Cancer Research, Center Institute, Seattle, USA

    Barry L. Stoddard

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