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  • Book
  • © 2005

Developmental Biology of Neoplastic Growth

  • First book discussing the relationship between tumour growth and the developmental stages of the organism, at the molecular, cellular, tissue, and organism levels

  • Challenges the current paradigm of the cancers-aging relationship

Part of the book series: Progress in Molecular and Subcellular Biology (PMSB, volume 40)

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eBook USD 169.00
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Softcover Book USD 219.00
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Hardcover Book USD 219.99
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Table of contents (9 chapters)

  1. Front Matter

    Pages I-XII
  2. The Hedgehog Signaling Pathway in Cancer

    • Janni Vestergaard, Mads Bak, Lars Allan Larsen
    Pages 1-28
  3. Rho GTPases and Cancer

    • Pinella Buongiorno, Bharati Bapat
    Pages 29-53
  4. Testicular Teratomas: Back to Pluripotent Stem Cells

    • Tohru Kimura, Kazushige Murayama, Toshinobu Nakamura, Shoko Watanabe, Hiroki Umehara, Maya Tomooka et al.
    Pages 133-150
  5. Tumor Suppressors APC and VHL: Gatekeepers of the Intestine and Kidney

    • Rachel H. Giles, Emile E. Voest
    Pages 151-181
  6. Hormonal and Stromal Regulation of Normal and Neoplastic Prostatic Growth

    • W.A. Ricke, Y. Wang, T. Kurita, S.W. Hayward, G.R. Cunha
    Pages 183-216
  7. Back Matter

    Pages 251-253

About this book

In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest. Several mechanisms are proposed to explain the distribution of cancers during the human life span and the decline of the incidence of cancers during human senescence.

Editors and Affiliations

  • INSERM, Versailles, France

    Alvaro Macieira-Coelho

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (Canada)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.00
Price excludes VAT (Canada)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (Canada)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access