Table of contents

  1. Front Matter
  2. Stephanie J. Moeller, Robert J. Sheaff
    Pages 1-29
  3. Jamie K. Teer, Anindya Dutta
    Pages 31-63
  4. Christopher P. Mattison, Mark Winey
    Pages 111-146
  5. Jan-Hermen Dannenberg, Hein P. J. te Riele
    Pages 183-225
  6. Hiroaki Kiyokawa
    Pages 257-270
  7. Eiman Aleem, Philipp Kaldis
    Pages 271-328
  8. Sandra Bernard, Martin Eilers
    Pages 329-342
  9. Changanamkandath Rajesh, Douglas L. Pittman
    Pages 343-367
  10. Back Matter

About this book


The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer.


Cyclin Cyclin-dependent kinase (CdK) DNA cancer research cell cycle regulation

Bibliographic information