Overview
- Presents an overall picture of the current state of knowledge in Systems Biology
- Designed to offer a state-of-the-art review with in – depth assessments and perspectives of post-genomic biology through understanding the molecular and cellular basis of integrated biological systems
- The various chapters are describing the necessary methodologies for performing systems biology research
- Provides understanding of the interrelations between different hierarchies of biological information
Part of the book series: Cell Engineering (CEEN, volume 5)
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About this book
A comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall picture of the current topics central to structural and functional genomics, proteomics, metabolomics and bioinformatics, including such hot topics as RNAi, metabolic engineering and unfolded protein response. It includes reviews of the cellular response of environmental modulation such as low temperature and osmolarity, critical assessments of the applications of metabolomics and fluxomics approaches, examination of the utility of modulation of key genes and a presentation of a theory of chemical organisation which provides a new view of the system's structure. The clearly written chapters by experts in the field describe methods applicable to investigating the unique facets of cell culture. The book should be of interest to all those working in cell culture development and drug discovery in pharmaceutical and biotechnology companies as well as in academic institutions. It provides an invaluable resource for students and researchers in biotechnology, cell culture, genomics and bioinformatics.
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Keywords
Table of contents (12 chapters)
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Front Matter
Reviews
From the reviews:
"This book is written for basic science and clinical researchers … . Biomedical scientists involved in genomics/proteomics research and drug discovery will also appreciate the wealth of information and interesting new concepts presented. … The chapters are well written and the topics are interesting. … the book is intended both for advanced students and experts in theoretical systems biology. … The authors illustrate their work nicely and provide general readers with a vision of future developments expected in cellular engineering." (Bruce A. Fenderson, Doody’s Review Service, August, 2008)
Editors and Affiliations
Bibliographic Information
Book Title: Systems Biology
Editors: Mohamed Al-Rubeai, Martin Fussenegger
Series Title: Cell Engineering
DOI: https://doi.org/10.1007/1-4020-5252-9
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2007
Hardcover ISBN: 978-1-4020-5251-4Published: 07 December 2006
Softcover ISBN: 978-90-481-7322-8Published: 17 November 2010
eBook ISBN: 978-1-4020-5252-1Published: 15 May 2007
Series ISSN: 1389-6946
Series E-ISSN: 2542-9515
Edition Number: 1
Number of Pages: VIII, 424
Topics: Proteomics, Protein Science, Microbiology, Bioinformatics, Cell Biology, Microbial Genetics and Genomics