Hedgehog-Gli Signaling in Human Disease

  • Ariel┬áRuiz i Altaba

Part of the Molecular Biology Intelligence Unit book series (MBIU)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Ariel Ruiz i Altaba
    Pages 1-22
  3. Luis Quijada, Ainhoa Callejo, Carlos Torroja, Isabel Guerrero
    Pages 23-33
  4. Henk Roelink
    Pages 34-40
  5. Fritz Aberger, Anna-Maria Frischauf
    Pages 74-85
  6. Pleasantine Mill, Chi-Chung Hui
    Pages 86-118
  7. Paul M. Fitch, Sonia J. Wakelin, Jacqueline A. Lowrey, William A. H. Wallace, Sarah E. M. Howie
    Pages 119-128
  8. Leslie G. Biesecker
    Pages 129-136
  9. Chin Chiang
    Pages 137-145
  10. M. Elizabeth McCready, Dennis E. Bulman
    Pages 146-152
  11. Dwight Cordero, Minal Tapadia, Jill A. Helms
    Pages 153-176
  12. Frederic J. de Sauvage, Lee L. Rubin
    Pages 210-214
  13. Marina Pasca di Magliano, Matthias Hebrok
    Pages 215-224
  14. Back Matter
    Pages 225-228

About this book


Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research. The chapters cover a wide spectrum of related interests, from the molecular bases of morphogen function, to human genetics to cancer research. The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine. This is a timely primer on how a system of cell communication, Hedgehog-GLI signaling, plays a critical role in human disease and thus provides the background for the development of novel and rational therapies.


Endoderm Tempo carcinoma genetics tumorigenesis

Authors and affiliations

  • Ariel┬áRuiz i Altaba
    • 1
  1. 1.Department of Genetic Medicine and DevelopmentUniversity of Geneva Medical SchoolGenevaSwitzerland

Bibliographic information