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DNA Conformation and Transcription

  • Takashi Ohyama

Part of the Molecular Biology Intelligence Unit book series (MBIU)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Multifarious DNA Structures Found In Genomes

    1. Front Matter
      Pages 1-1
    2. DNA
      Vladimir N. Potaman, Richard R. Sinden
      Pages 3-17
    3. Victor B. Zhurkin, Michael Y. Tolstorukov, Fei Xu, Andrew V. Colasanti, Wilma K. Olson
      Pages 18-34
  3. Intrinsic DNA Curvature and Transcription

    1. Front Matter
      Pages 35-35
    2. Munehiko Asayama, Takashi Ohyama
      Pages 37-51
    3. Cynthia L. Pon, Stefano Stella, Claudio O. Gualerzi
      Pages 52-65
    4. Takashi Ohyama
      Pages 66-74
    5. Jaime F. Angulo, Philippe Mauffirey, Ghislaine Pinon-Lataillade, Laurent Miccoli, Denis S. F. Biard
      Pages 75-89
  4. Implied Roles of Left-Handed Z-DNA, Triplex DNA, DNA Supercoiling, and Miscellaneous Alternative Conformations of DNA in Transcription

  5. DNA-Bending Proteins: Architectural Regulation of Transcription

  6. Chromatin Infrastructure in Transcription: Roles of DNA Conformation and Properties

    1. Front Matter
      Pages 175-175
    2. Mensur Dlakić, David W. Ussery, Søren Brunak
      Pages 189-202
  7. Back Matter
    Pages 203-211

About this book

Introduction

Despite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differential expression of genes is enabled in a given cell type. Exploring and answering these questions constitutes one of the next frontiers in the 21st century.

We are just beginning to appreciate how Multifarious DNA structures provide additional structural and functional dimensions to chromatin organization and gene expression. DNA Conformation and Transcription is the first book that compiles the fruits of the studies that have been performed to date to solve the riddle ‘written’ in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code".

Keywords

Chromosom DNA Promoter RNA Termination gene expression genes molecular mechanisms proteins regulation transcription

Authors and affiliations

  • Takashi Ohyama
    • 1
  1. 1.Department of Biology Faculty of Science and EngineeringKonan UniversityKobeJapan

Bibliographic information