Table of contents

  1. Front Matter
  2. Marcus J.O. Johansson, Anders S. Byström
    Pages 87-120
  3. James T. Anderson, Louis Droogmans
    Pages 121-139
  4. Achim Dickmanns, Ralf Ficner
    Pages 179-204
  5. Yi-Tao Yu, Rebecca M. Terns, Michael P. Terns
    Pages 223-262
  6. Stephen Douthwaite, Dominique Fourmy, Satoko Yoshizawa
    Pages 285-307
  7. Olivier Namy, François Lecointe, Henri Grosjean, Jean-Pierre Rousset
    Pages 309-340
  8. Barry Hoopengardner, Mary A. O’Connell, Robert Reenan, Liam P. Keegan
    Pages 341-364
  9. Harold C. Smith, Joseph E. Wedekind, Kefang Xie, Mark P. Sowden
    Pages 365-400
  10. Roland Marquet, Frédéric Dardel
    Pages 401-429
  11. Bradley A. Carlson, Xue-Ming Xu, Vadim N. Gladyshev, Dolph L. Hatfield
    Pages 431-438
  12. Back Matter

About this book


Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process designated RNA modification. A large number of enzymes catalyzing the formation of these modified nucleosides or converting one canonical base into another at the posttranscriptional level have been studied for many years, but only recently have systematic and comparative studies begun. The functions of individual enzymes and/or the modified/edited nucleosides in RNA, however, have remained largely ignored.

This book provides advance information on RNA modification, including the associated editing machinery, while offering the reader some perspective on the significance of such modifications in fine-tuning the structure and functions of mature RNA molecules and hence the ability to influence the efficiency and accuracy of genetic expression. Outstanding scientists who are actively working on RNA modification/editing processes have provided up-to-date information on these intriguing cellular processes that have been generated over the course of millions of years in all living organisms. Each review has been written and illustrated for a large audience of readers, not only specialists in the field, but also for advanced students or researchers who want to learn more about recent progress in RNA modification and editing.


DNA Nucleotide RNA base cellular processes enzyme enzymes influence methylation protein proteins ribosome biogenesis tRNA transcription translation

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin/Heidelberg 2005
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-24495-0
  • Online ISBN 978-3-540-31454-7
  • Series Print ISSN 1610-2096
  • Series Online ISSN 1610-6970
  • Buy this book on publisher's site