Oxidative Phosphorylation in Health and Disease

  • Jan A. M. Smeitink
  • Rob C. A. Sengers
  • J. M. Frans Trijbels

Part of the Medical Intelligence Unit book series (MIUN)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Immo E. Scheffler
    Pages 1-27
  3. Richard C. Scarpulla
    Pages 28-42
  4. Robert McFarland, Patrick F. Chinnery, Robert W. Taylor, Andrew M. Schaefer, Douglass M. Turnbull
    Pages 43-52
  5. J. M. Frans Trijbels, Antoon J. M. Janssen, Lambert P. van den Heuvel, Rob C. A. Sengers, Jan A. M. Smeitink
    Pages 79-94
  6. Massimo Zeviani, Valerio Carelli
    Pages 95-116
  7. Lambert P. van den Heuvel, Jan A. M. Smeitink
    Pages 117-129
  8. Werner J. H. Koopman, Henk-Jan Visch, Sjoerd Verkaart, Peter H. G. M. Willems
    Pages 130-148
  9. Nicole Hance, Nils-Göran Larsson
    Pages 149-169
  10. Rob C. A. Sengers, J. M. Frans Trijbels, Carolien C. A. Boelen, Eva Morava, Jan A. M. Smeitink
    Pages 170-175
  11. Antoon J. M. Janssen, Letitia E. M. Niers, Lambert P. van den Heuvel, Jan A. M. Smeitink, Rob C. A. Sengers, J. M. Frans Trijbels
    Pages 176-186
  12. Back Matter
    Pages 201-205

About this book


Mitochondrial diseases are often hard to diagnose. From the time they were first researched without animal models, patients of mitochondrial diseases were of equal interest to both clinical and basic scientists. With the new research done, this book includes updates on the normal structure, function, and molecular biology of the mitochondrial respiratory chain, information on traditional diagnostical methodologies, and an overview of the diagnostic promise of new technologies. The hypermetabolism of Luft disease, although only seen twice, is also studied. There are critical reviews of symptoms and signs associated with syndromes, as well as updates on the genetic defects of either the mitochondrial or the nuclear genome responsible for many disorders.


DNA RNA biochemistry biology cell development diagnostics genetics genome metabolism mitochondria molecular biology physiology tissue transcription

Authors and affiliations

  • Jan A. M. Smeitink
    • 1
  • Rob C. A. Sengers
    • 1
  • J. M. Frans Trijbels
    • 1
  1. 1.Department of PediatricsNijmegen Center for Mitochondrial Disorders University Medical Center NijmegenNijmegenThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information / Kluwer Academic / Plenum Publishers 2005
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-0-306-48232-8
  • Online ISBN 978-0-387-26992-4
  • Buy this book on publisher's site